Fu Steven S, Okuyemi Kolawole S, Partin Melissa R, Ahluwalia Jasjit S, Nelson David B, Clothier Barbara A, Joseph Anne M
Physician Research Fellowship Program, Center for Chronic Disease Outcomes Research (a VA HSR&D Center of Excellence), Veterans Affairs Medical Center, Minneapolis, MN 55417, USA.
Nicotine Tob Res. 2008 Mar;10(3):457-62. doi: 10.1080/14622200801901914.
Menthol may make cigarettes more addictive and rates of menthol cigarette smoking are disproportionately higher among Black. However, few studies have examined the association between menthol cigarette smoking and cessation, and the studies to date have produced conflicting findings. The present study examines the effect of menthol cigarette smoking on cessation among a multi-ethnic sample of smokers making a pharmacotherapy-aided quit attempt. We hypothesized that menthol cigarette smoking would be associated with lower smoking abstinence rates and conducted a secondary analysis of data from a multi-site randomized controlled trial of an intervention designed to facilitate repeat tobacco cessation treatment (N = 1,343). The intervention consisted of a patient phone call and a computerized provider prompt. The primary outcome for this analysis was 7-day point prevalence smoking abstinence. The average age of the sample was 56 years old. Overall, 25% of the sample smoked menthol cigarettes: 19% of Whites, 62% of Blacks, and 25% of other ethnicity (p<.001). We observed no significant effects for menthol cigarette smoking or ethnicity on smoking abstinence rates. In conclusion, combined with findings from previous research, this study suggests that smoking menthol cigarettes does not decrease smoking cessation among older smokers during a quit attempt aided with pharmacotherapy.
薄荷醇可能会使香烟更易成瘾,并且黑人中薄荷醇香烟的吸烟率不成比例地更高。然而,很少有研究考察薄荷醇香烟吸烟与戒烟之间的关联,而且迄今为止的研究结果相互矛盾。本研究考察了在一个进行药物辅助戒烟尝试的多民族吸烟者样本中,吸薄荷醇香烟对戒烟的影响。我们假设吸薄荷醇香烟会与较低的戒烟率相关,并对一项旨在促进重复戒烟治疗的多中心随机对照试验(N = 1343)的数据进行了二次分析。该干预包括患者电话随访和计算机化的医生提醒。本次分析的主要结局是7天的时点患病率戒烟情况。样本的平均年龄为56岁。总体而言,25%的样本吸薄荷醇香烟:19%的白人、62%的黑人以及25%的其他种族(p<.001)。我们观察到吸薄荷醇香烟或种族对戒烟率没有显著影响。总之,结合先前研究的结果,本研究表明在药物辅助的戒烟尝试期间,吸薄荷醇香烟不会降低老年吸烟者的戒烟率。