Gabilondo Fernando, Rodríguez Francisco, Mohar Alejandro, Nuovo Gerald J, Domínguez-Malagón Hugo
Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Mexico City, Mexico.
Ann Diagn Pathol. 2008 Apr;12(2):134-7. doi: 10.1016/j.anndiagpath.2006.08.005. Epub 2007 Jul 24.
Synovial sarcoma is a tumor of the soft tissues with a unique chromosomal translocation t(X;18)(p 11.2;q11.2) that can be detected by polymerase chain reaction in tissue homogenates. The case of a 32-year-old woman with a primary synovial sarcoma of the kidney is described, the diagnosis was corroborated by the recently developed method of in situ polymerase chain reaction (IS-PCR). Synovial sarcoma of the kidney may be confused with other spindle cell tumors, for that reason IS-PCR may be useful to confirm the diagnosis in paraffin-embedded material.
滑膜肉瘤是一种软组织肿瘤，具有独特的染色体易位t(X;18)(p11.2;q11.2)，可通过聚合酶链反应在组织匀浆中检测到。本文描述了一名32岁患有原发性肾滑膜肉瘤的女性病例，诊断通过最近开发的原位聚合酶链反应（IS-PCR）方法得到证实。肾滑膜肉瘤可能与其他梭形细胞瘤混淆，因此IS-PCR可能有助于在石蜡包埋材料中确诊。
