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男性患者的肝腺瘤。

Hepatic adenomas in male patients.

机构信息

Hepatobiliary and Upper Gastrointestinal Unit, Department of Surgery, Auckland Hospital, Auckland, New Zealand.

出版信息

HPB (Oxford). 2004;6(1):25-7. doi: 10.1080/13651820310020846.

DOI:10.1080/13651820310020846
PMID:18333041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2020650/
Abstract

BACKGROUND

Hepatic adenomas are benign tumours of the liver most commonly seen in premenopausal women. However, it is now clear that adenomas may occur in males. This small series reviews the characteristics of hepatic adenomas in males.

CASE OUTLINES

Three cases of solitary hepatic adenoma occurring in otherwise well male patients (age 22-48 years) are presented. Two patients presented with abnormal liver function tests while one presented with abdominal pain. Imaging of the lesions demonstrated typical appearances of hepatocellular adenoma, resection was undertaken in all cases and all patients remain alive and well.

DISCUSSION

Up to 20% of adenomas are documented as occurring in male patients. Most are solitary and occur in patients without recognised risk factors (steroid therapy and glycogen storage diseases types I and III). However, multiple adenomas are most commonly seen in male patients with risk factors. The imaging characteristics and presentation of adenomas in males are similar to female patients and, most importantly, intraperitoneal rupture and malignant transformation are documented in untreated adenomas in males.

摘要

背景

肝腺瘤是肝脏的良性肿瘤,最常见于绝经前妇女。然而,现在已经清楚,腺瘤也可能发生在男性中。本小系列回顾了男性肝腺瘤的特征。

病例概述

介绍了 3 例单发肝腺瘤,发生在其他情况良好的男性患者(年龄 22-48 岁)中。2 例患者出现肝功能异常,1 例患者出现腹痛。病变的影像学表现为典型的肝细胞腺瘤表现,所有病例均行切除术,所有患者均存活且状况良好。

讨论

多达 20%的腺瘤被记录为发生在男性患者中。大多数是单发的,发生在没有已知危险因素(类固醇治疗和糖原贮积病 I 型和 III 型)的患者中。然而,多发腺瘤最常见于有危险因素的男性患者中。男性腺瘤的影像学特征和表现与女性患者相似,最重要的是,未治疗的男性腺瘤中存在腹腔内破裂和恶性转化。

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2
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本文引用的文献

1
Liver cell adenoma in a 26-year-old man.一名26岁男性的肝细胞腺瘤。
J Nippon Med Sch. 2001 Dec;68(6):516-9. doi: 10.1272/jnms.68.516.
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Differentiation of liver cell adenomas from well-differentiated hepatocellular carcinomas by comparative genomic hybridization.通过比较基因组杂交技术鉴别肝细胞腺瘤与高分化肝细胞癌
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Treatment of ruptured hepatocellular adenoma.破裂肝细胞腺瘤的治疗。
Br J Surg. 2001 Feb;88(2):207-9. doi: 10.1046/j.1365-2168.2001.01648.x.
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Clinicopathological characteristics of surgically resected minute hepatocellular carcinomas.手术切除微小肝细胞癌的临床病理特征
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Hepatocellular adenoma: multiphasic CT and histopathologic findings in 25 patients.肝细胞腺瘤:25例患者的多期CT及组织病理学表现
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Benign liver tumors: differential diagnosis and indications for surgery.良性肝肿瘤:鉴别诊断与手术指征
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Hepatic adenoma: MR characteristics and correlation with pathologic findings.肝腺瘤:磁共振成像特征及其与病理结果的相关性。
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Hepatic adenoma: MR findings in 51 pathologically proved lesions.肝腺瘤:51例经病理证实病变的磁共振成像表现
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Benign hepatic tumors: focal nodular hyperplasia and hepatocellular adenoma.良性肝肿瘤:局灶性结节性增生和肝细胞腺瘤。
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The malignant transformation of liver cell adenomas.肝细胞腺瘤的恶性转化。
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