Hepatobiliary and Upper Gastrointestinal Unit, Department of Surgery, Auckland Hospital, Auckland, New Zealand.
HPB (Oxford). 2004;6(1):25-7. doi: 10.1080/13651820310020846.
Hepatic adenomas are benign tumours of the liver most commonly seen in premenopausal women. However, it is now clear that adenomas may occur in males. This small series reviews the characteristics of hepatic adenomas in males.
Three cases of solitary hepatic adenoma occurring in otherwise well male patients (age 22-48 years) are presented. Two patients presented with abnormal liver function tests while one presented with abdominal pain. Imaging of the lesions demonstrated typical appearances of hepatocellular adenoma, resection was undertaken in all cases and all patients remain alive and well.
Up to 20% of adenomas are documented as occurring in male patients. Most are solitary and occur in patients without recognised risk factors (steroid therapy and glycogen storage diseases types I and III). However, multiple adenomas are most commonly seen in male patients with risk factors. The imaging characteristics and presentation of adenomas in males are similar to female patients and, most importantly, intraperitoneal rupture and malignant transformation are documented in untreated adenomas in males.
肝腺瘤是肝脏的良性肿瘤,最常见于绝经前妇女。然而,现在已经清楚,腺瘤也可能发生在男性中。本小系列回顾了男性肝腺瘤的特征。
介绍了 3 例单发肝腺瘤,发生在其他情况良好的男性患者(年龄 22-48 岁)中。2 例患者出现肝功能异常,1 例患者出现腹痛。病变的影像学表现为典型的肝细胞腺瘤表现,所有病例均行切除术,所有患者均存活且状况良好。
多达 20%的腺瘤被记录为发生在男性患者中。大多数是单发的,发生在没有已知危险因素(类固醇治疗和糖原贮积病 I 型和 III 型)的患者中。然而,多发腺瘤最常见于有危险因素的男性患者中。男性腺瘤的影像学特征和表现与女性患者相似,最重要的是,未治疗的男性腺瘤中存在腹腔内破裂和恶性转化。