Benoist G, Jacquemard F, Leruez-Ville M, Ville Y
Service de gynécologie-obstétrique, centre hospitalier intercommunal (CHI) de Poissy Saint-Germain, 10 rue du Champ-Gaillard, Poissy, France.
Gynecol Obstet Fertil. 2008 Mar;36(3):248-60. doi: 10.1016/j.gyobfe.2008.01.004. Epub 2008 Mar 11.
Human Cytomegalovirus (CMV) is the main cause of mental retardation and sensorineural hearing loss related to congenital infections. Justification of systematic screening for fetal CMV infection is still controversial and is not recommended in most developed countries. This is mainly justified by the paucity of antenatal prognostic factors and the lack of established intrauterine treatment when fetal infection has been diagnosed. Our aim was to review the current state of the knowledge about the CMV congenital infection and to highlight recent advances in the diagnosis as well as in the identification of prognostic factors.
人类巨细胞病毒（CMV）是先天性感染所致智力迟钝和感音神经性听力损失的主要病因。对于胎儿CMV感染进行系统筛查的合理性仍存在争议，且在大多数发达国家并不推荐。这主要是由于产前预后因素较少，以及在诊断胎儿感染后缺乏成熟的宫内治疗方法。我们的目的是回顾关于CMV先天性感染的当前知识状况，并强调在诊断以及预后因素识别方面的最新进展。
