Milewska-Bobula Bogumiła, Lipka Bozena
Klinika Niemowleca Instytutu Pomnik-Centrum Zdrowia Dziecka w Warszawie.
Przegl Epidemiol. 2009;63(1):79-83.
Authors presented of a cytomegalovirus characteristics, its existing in human population and rare clinical presentation in immunocompetent persons (including pregnant women) after primary infection. The vertical transmission from mother to the fetus and the mode of acquisition of infection in perinatal period as well as symptoms of congenital cytomegaly together with late sequelae are also under discussion. Authors stressed, that advances in improvements in the diagnosis of maternal, fetal and newborn infection are not outpaced with improvements in the antiviral treatment of fetuses and infants, but improvement or stabilization of hearing loss after ganciclovir therapy is observed. Routine serologic screening for an immunity (mothers and newborns) is still controversial. At present, the prevention of CMV infection is the ideal solution, especially the education people about CMV and routes of transmission.
作者介绍了巨细胞病毒的特征、其在人群中的存在情况以及在初次感染后免疫功能正常者（包括孕妇）中罕见的临床表现。还讨论了从母亲到胎儿的垂直传播、围产期感染的获得方式、先天性巨细胞病毒的症状以及晚期后遗症。作者强调，在胎儿和婴儿抗病毒治疗方面的进展并未超过对母亲、胎儿和新生儿感染诊断的改善，但观察到更昔洛韦治疗后听力损失有所改善或稳定。对（母亲和新生儿）免疫情况进行常规血清学筛查仍存在争议。目前，预防巨细胞病毒感染是理想的解决方案，尤其是对人们进行有关巨细胞病毒及其传播途径的教育。
