[素馨花（大花茉莉）花蕾中的三萜皂苷]

[Triterpenoid saponins from flower bud of Jasminum officinale var. grandiflorum].

作者信息

Zhao Gui-Qin, Dong Jun-Xing

机构信息

Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Jan;33(1):38-42.

PMID:18338617

Abstract

OBJECTIVE

To study the chemical constituent bud of the flowers of Jasminum officinale var. grandiflorum.

METHOD

The compounds were isolated and purified by recrystallization and chromatography on silica gel and Sephadex LH - 20 column. Their structures were elucidated on the basis of physicochemical properties and spectral analysis.

RESULT

Six triterpenoid saponins were identified as 3-O-alpha-L-rhamnopyranosyl (1 --> 2)-beta-D-xylopyranosyl- hederagenin-28-O-beta-D-galactopyranosyl (1 --> 6)-beta-D-galactopyranosyl ester (1), hederagenin-3-O-beta-D-glucopyranosyl (1 --> 3)-alpha-L-arabinopyranoside (2), 2alpha, 3beta, 23-trihydroxyolean-12-en-28-oic-O-beta-D-glucopyranosyl ester (3), hederagenin-3-O-beta-D-xylopyranosyl (1 --> 3)-alpha-L-rhamnopyranosyl (1 --> 2)-alpha-L-arabinopyranoside (4), 2alpha, 3beta, 23-trihydroxyolean-12-en-28-oic-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranosyl ester (5), hederagenin-3-O-alpha-L-rhamnopyranosyl (1 --> 2)-alpha-L-arabinopyranoside (6).

CONCLUSION

Compound 1 is a new compound. Compounds 2, 3, 4, 5, 6 were isolated from the genus Jasminum for the first time.

摘要

目的

研究大花素馨花的化学成分。

方法

通过重结晶以及硅胶柱色谱和葡聚糖凝胶LH - 20柱色谱对化合物进行分离和纯化。根据其理化性质和光谱分析确定其结构。

结果

鉴定出6个三萜皂苷，分别为3 - O-α-L-鼠李吡喃糖基（1→2）-β-D-木吡喃糖基-常春藤皂苷元-28 - O-β-D-半乳吡喃糖基（1→6）-β-D-半乳吡喃糖基酯（1）、常春藤皂苷元-3 - O-β-D-葡萄糖吡喃糖基（1→3）-α-L-阿拉伯吡喃糖苷（2）、2α，3β，23 - 三羟基齐墩果-12 - 烯-28 - 酸-O-β-D-葡萄糖吡喃糖基酯（3）、常春藤皂苷元-3 - O-β-D-木吡喃糖基（1→3）-α-L-鼠李吡喃糖基（1→2）-α-L-阿拉伯吡喃糖苷（4）、2α，3β，23 - 三羟基齐墩果-12 - 烯-28 - 酸-O-α-L-鼠李吡喃糖基（1→4）-β-D-葡萄糖吡喃糖基（1→6）-β-D-葡萄糖吡喃糖基酯（5）、常春藤皂苷元-3 - O-α-L-鼠李吡喃糖基（1→2）-α-L-阿拉伯吡喃糖苷（6）。