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大花茉莉(木犀科)的植物药理学概况

Phytopharmacological Profile of Jasminum grandiflorum Linn. (Oleaceae).

作者信息

Arun Mittal, Satish Sardana, Anima Pandey

机构信息

Hindu College of Pharmacy, Sonipat, Haryana, 131001, India.

Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, 835215, India.

出版信息

Chin J Integr Med. 2016 Apr;22(4):311-20. doi: 10.1007/s11655-015-2051-3. Epub 2015 Apr 6.

Abstract

Plants are the real basis towards animal life and are also central to people's livelihood. The contributions of the plants in performing varied religious celebrations and in other multiple beneficiaries like medicine, human happiness as well as in treating deadly diseases can never be neglected. In treating diseases, the plants and their constituents are better choice than any other synthetic chemical. The nature has been kind enough to provide the human beings with various types of medicinal plants and in the real sense these form the storehouse of curing almost all the ailments. Consequently, most of the drugs which are being used in preparing formulations have their origin and roots in the plants which form the chief natural source of medicines. Even in modern era, the plant-derived drugs are being extensively used, either in their original or semi-synthetic form. It is because their natural phytoconstituents are highly innocuous posing relatively fewer or no side effects. Based upon their observations, analysis and experience, our ancestors used many plants for medicinal purposes and thus their efforts need to be supported by scientific evidence. Jasminum grandiflorum Linn. is one of such important plants. It has been extensively used by the tribes all over India to treat different diseases which mainly include body pains, toothache, stomach ache, ulcers, and sexual impotency. Chemistry of the plant revealed the presence of mainly secoiridoids, terpenoids, flavonoids and tannins. Not much scientific support was given to the folklore claims for this plant but some of its traditional uses were investigated like spasmolytic, wound healing, antimicrobial, angiotensin converting enzyme inhibitor, antiulcer and antioxidant activities. This article is the review of research works done on the plant Jasminum grandiflorum Linn. to date. As a part of it the local names, morphology, traditional claims, chemistry and pharmacological activities have been discussed.

摘要

植物是动物生命的真正基础,也是人类生计的核心。植物在各种宗教庆典以及医学、人类幸福等其他诸多有益方面的贡献,以及在治疗致命疾病方面的作用,绝不能被忽视。在治疗疾病方面,植物及其成分比任何其他合成化学物质都是更好的选择。大自然慷慨地为人类提供了各种药用植物,实际上这些植物构成了治疗几乎所有疾病的宝库。因此,大多数用于制备制剂的药物都起源于植物,植物是药物的主要天然来源。即使在现代,植物衍生药物仍被广泛使用,无论是其原始形式还是半合成形式。这是因为它们天然的植物成分高度无害,副作用相对较少或没有。基于他们的观察、分析和经验,我们的祖先使用了许多植物来治病,因此他们的努力需要科学证据的支持。大花茉莉就是这样一种重要的植物。印度各地的部落广泛使用它来治疗各种疾病,主要包括身体疼痛、牙痛、胃痛、溃疡和性功能障碍。对该植物的化学分析表明,其主要含有裂环环烯醚萜类、萜类、黄酮类和单宁。对于这种植物的民间说法,科学支持并不多,但对它的一些传统用途进行了研究,如解痉、伤口愈合、抗菌、血管紧张素转换酶抑制、抗溃疡和抗氧化活性。本文是对迄今为止关于大花茉莉的研究工作的综述。作为其中一部分,讨论了它的当地名称、形态、传统说法、化学和药理活性。

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