St Sauver Jennifer L, Jacobson Debra J, McGree Michaela E, Girman Cynthia J, Lieber Michael M, Jacobsen Steven J
Urology. 2008 Mar;71(3):475-9; discussion 479. doi: 10.1016/j.urology.2007.11.155.
To determine whether physician-diagnosed prostatitis was associated with later development of benign prostatic hyperplasia (BPH)-associated events in a longitudinal, population-based sample of 2447 men residing in Olmsted County, Minnesota.
Medical records were reviewed for physician diagnosis of prostatitis and subsequent diagnoses of BPH, enlarged prostate, prostatism, and acute urinary retention. Records were also reviewed for medical or surgical treatments for BPH. Odds ratios were calculated to assess the associations between physician-diagnosed prostatitis and later development of development of BPH-associated events.
Physician-diagnosed prostatitis was associated with a 2.4-fold increased odds of receiving a later diagnosis of prostatism, enlarged prostate, or BPH (OR: 2.44, 95% CI: 1.48, 4.01). Prostatitis was also associated with a 70% increased odds of requiring later treatment for BPH (OR: 1.69, 95% CI: 1.28, 2.22), and a non-significant increased odds of acute urinary retention (OR: 1.33, 95% CI: 0.89, 1.99).
Physician-diagnosed prostatitis was associated with an increased risk of later onset of several BPH-associated events. Physician-diagnosed prostatitis may therefore be an early marker or a risk factor for development of later prostatic or urologic problems.
在明尼苏达州奥姆斯特德县居住的2447名男性的纵向、基于人群的样本中，确定医生诊断的前列腺炎是否与随后良性前列腺增生（BPH）相关事件的发生有关。
回顾医疗记录，以了解医生对前列腺炎的诊断以及随后对BPH、前列腺肿大、前列腺增生和急性尿潴留的诊断。还回顾了BPH的药物或手术治疗记录。计算比值比以评估医生诊断的前列腺炎与随后BPH相关事件发生之间的关联。
医生诊断的前列腺炎与随后被诊断为前列腺增生、前列腺肿大或BPH的几率增加2.4倍相关（比值比：2.44，95%置信区间：1.48，4.01）。前列腺炎还与随后需要进行BPH治疗的几率增加70%相关（比值比：1.69，95%置信区间：1.28，2.22），以及急性尿潴留的几率增加但不显著（比值比：1.33，95%置信区间：0.89，1.99）。
医生诊断的前列腺炎与随后发生几种BPH相关事件的风险增加有关。因此，医生诊断的前列腺炎可能是后期前列腺或泌尿系统问题发生的早期标志物或危险因素。
