Posner Jonathan, Russell James A, Gerber Andrew, Gorman Daniel, Colibazzi Tiziano, Yu Shan, Wang Zhishun, Kangarlu Alayar, Zhu Hongtu, Peterson Bradley S
Columbia College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA.
Hum Brain Mapp. 2009 Mar;30(3):883-95. doi: 10.1002/hbm.20553.
We aimed to study the neural processing of emotion-denoting words based on a circumplex model of affect, which posits that all emotions can be described as a linear combination of two neurophysiological dimensions, valence and arousal. Based on the circumplex model, we predicted a linear relationship between neural activity and incremental changes in these two affective dimensions.
Using functional magnetic resonance imaging, we assessed in 10 subjects the correlations of BOLD (blood oxygen level dependent) signal with ratings of valence and arousal during the presentation of emotion-denoting words.
Valence ratings correlated positively with neural activity in the left insular cortex and inversely with neural activity in the right dorsolateral prefrontal and precuneus cortices. The absolute value of valence ratings (reflecting the positive and negative extremes of valence) correlated positively with neural activity in the left dorsolateral and medial prefrontal cortex (PFC), dorsal anterior cingulate cortex, posterior cingulate cortex, and right dorsal PFC, and inversely with neural activity in the left medial temporal cortex and right amygdala. Arousal ratings and neural activity correlated positively in the left parahippocampus and dorsal anterior cingulate cortex, and inversely in the left dorsolateral PFC and dorsal cerebellum.
We found evidence for two neural networks subserving the affective dimensions of valence and arousal. These findings clarify inconsistencies from prior imaging studies of affect by suggesting that two underlying neurophysiological systems, valence and arousal, may subserve the processing of affective stimuli, consistent with the circumplex model of affect.
我们旨在基于情感环形模型研究表示情感的词汇的神经加工过程，该模型假定所有情感都可描述为效价和唤醒这两个神经生理维度的线性组合。基于该环形模型，我们预测神经活动与这两个情感维度的增量变化之间存在线性关系。
我们使用功能磁共振成像技术，在10名受试者中评估了表示情感的词汇呈现期间血氧水平依赖（BOLD）信号与效价和唤醒评分之间的相关性。
效价评分与左侧岛叶皮质的神经活动呈正相关，与右侧背外侧前额叶皮质和楔前叶皮质的神经活动呈负相关。效价评分的绝对值（反映效价的正负极端情况）与左侧背外侧和内侧前额叶皮质（PFC）、背侧前扣带回皮质、后扣带回皮质以及右侧背侧PFC的神经活动呈正相关，与左侧内侧颞叶皮质和右侧杏仁核的神经活动呈负相关。唤醒评分与神经活动在左侧海马旁回和背侧前扣带回皮质呈正相关，在左侧背外侧PFC和背侧小脑呈负相关。
我们发现了支持效价和唤醒情感维度的两个神经网络的证据。这些发现通过表明两个潜在的神经生理系统，即效价和唤醒，可能参与情感刺激的加工，澄清了先前情感成像研究中的不一致之处，这与情感环形模型一致。
