Shimokawa I, Yu B P, Masoro E J
First Department of Pathology, Nagasaki University Medical School, Japan.
J Gerontol. 1991 Nov;46(6):B228-32. doi: 10.1093/geronj/46.6.b228.
The influence of dietary manipulations on fatal neoplasms in male Fischer 344 rats was assessed. Particular attention was paid to leukemia and pituitary adenoma because they are the most common potentially fatal neoplasms that occur in this rat strain. The only dietary manipulation which depressed the mortality rates due to neoplastic disease was that involving a reduction in energy intake. Reduction of mineral or protein or fat intake without a reduction of energy had, at most, marginal effects on fatal neoplastic disease.
评估了饮食干预对雄性Fischer 344大鼠致命性肿瘤的影响。特别关注白血病和垂体腺瘤，因为它们是该大鼠品系中最常见的潜在致命性肿瘤。唯一能降低肿瘤疾病死亡率的饮食干预是减少能量摄入。在不减少能量的情况下减少矿物质、蛋白质或脂肪的摄入，对致命性肿瘤疾病最多只有微不足道的影响。
