Vasconcellos Luana M R, Oliveira Marize V, Graça Mário L A, Vasconcellos Luis G O, Cairo Carlos A A, Carvalho Yasmin R
Department of Bioscience and Buccal Diagnosis, State University of Sao Paulo (UNESP), Sao Jose dos Campos, Brazil.
J Mater Sci Mater Med. 2008 Aug;19(8):2851-7. doi: 10.1007/s10856-008-3421-6. Epub 2008 Mar 18.
The fixation and the bone ingrowth at the interface of porous cylindrical implants (total porosity of 37% and average pores diameter of 480 microm) were compared in vivo to rough cylindrical implants (R (a) = 5.3 microm), both of commercially pure titanium, made by powder metallurgy. The implants were inserted into the tibias of 20 rabbits and the animals were sacrificed 4 and 8 weeks after surgery. The percentage of bone-implant contact observed in porous implant was significantly larger than in the rough ones for all of sacrifice periods, respectively, 57% vs. 46% after 4 weeks, and 59% vs. 50% after 8 weeks. The mechanical tests showed a significant increase in the shear strength of the porous implants for the two analyzed periods, 4 and 8 weeks (14 and 20 MPa), when compared with rough ones (4 and 13 MPa). These results suggest that porous implants improve the contact at the implant-bone interface and increase the fixation to the bone, improving the osseointegration. Thus, the porous implant might be an alternative to dental implant in less favorable conditions, and appear to be better fixed to bone, offering promising alternatives.
在体内比较了多孔圆柱形植入物(总孔隙率为37%,平均孔径为480微米)与粗糙圆柱形植入物(R (a) = 5.3微米)在界面处的固定和骨长入情况,这两种植入物均由粉末冶金法制成,材质均为商业纯钛。将植入物植入20只兔子的胫骨中,术后4周和8周处死动物。在所有处死时间段,多孔植入物中观察到的骨-植入物接触百分比均显著高于粗糙植入物,术后4周分别为57%对46%,术后8周分别为59%对50%。力学测试表明,与粗糙植入物(4和13兆帕)相比,在分析的两个时间段(4周和8周),多孔植入物的剪切强度显著增加(分别为14和20兆帕)。这些结果表明,多孔植入物改善了植入物-骨界面的接触,增加了与骨的固定,改善了骨整合。因此,在不太有利的条件下,多孔植入物可能是牙种植体的一种替代选择,并且似乎与骨的固定更好,提供了有前景的替代方案。