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在皮肤组织模型中传播的会聚光束上粗糙界面效应的建模。

Modeling of the rough-interface effect on a converging light beam propagating in a skin tissue phantom.

作者信息

Lu J Q, Hu X H, Dong K

出版信息

Appl Opt. 2000 Nov 1;39(31):5890-7. doi: 10.1364/ao.39.005890.

DOI:10.1364/ao.39.005890
PMID:18354593
Abstract

Light distribution in a strong turbid medium such as skin tissue depends on both the bulk optical properties and the profiles of the interfaces where mismatch in the refractive index occurs. We present recent results of a numerical investigation on the light distribution inside a human skin tissue phantom for a converging laser beam with a wavelength near 1 mum and its dependence on the roughness of the interfaces and index mismatch. The skin tissue is modeled by a two-layer structure, and within each layer the tissue is considered macroscopically homogeneous. The two interfaces that separate the epidermis from the ambient medium and the dermis are considered randomly rough. With a recently developed method of Monte Carlo simulation capable of treating inhomogeneous boundary conditions, light distributions in various cases of interface roughness and index mismatch are obtained, and their relevance to the measurements of optical parameters of the skin tissue and laser surgery under the skin surface are discussed.

摘要

在诸如皮肤组织这样的强散射介质中,光的分布既取决于整体光学特性,也取决于折射率发生不匹配的界面轮廓。我们展示了一项数值研究的最新结果,该研究针对波长接近1微米的会聚激光束在人体皮肤组织模型内的光分布,以及其对界面粗糙度和折射率不匹配的依赖性。皮肤组织由两层结构建模,并且在每一层内,组织被视为宏观均匀的。将表皮与周围介质以及真皮分隔开的两个界面被认为是随机粗糙的。利用一种最近开发的能够处理非均匀边界条件的蒙特卡罗模拟方法,获得了各种界面粗糙度和折射率不匹配情况下的光分布,并讨论了它们与皮肤组织光学参数测量以及皮肤表面下激光手术的相关性。

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