Sello Jason K, Buttner Mark J
Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Colney, NR4 7UH Norwich, United Kingdom.
J Bacteriol. 2008 Jun;190(11):4079-83. doi: 10.1128/JB.01889-07. Epub 2008 Mar 21.
Phenotypic analysis of a constructed RNase III null mutant of Streptomyces coelicolor revealed that RNase III is required for both antibiotic production and proper formation of sporulation septa. Transcriptional analysis of the gene encoding RNase III indicated that it is transcribed exclusively during exponential phase as part of a tricistronic message.
对构建的天蓝色链霉菌RNase III基因缺失突变体进行的表型分析表明,抗生素生产和孢子形成隔膜的正常形成都需要RNase III。对编码RNase III的基因进行转录分析表明,它作为一个三顺反子信息的一部分,仅在指数生长期转录。