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择期开放腹主动脉瘤修复术:七年经验。

Elective open abdominal aortic aneurysm repair: a seven-year experience.

机构信息

Discipline of Surgical Science, Faculty of Health, The University of Newcastle and Clinical Governance Unit, Hunter Area Health Service NSW, Australia.

出版信息

Ther Clin Risk Manag. 2005 Mar;1(1):27-31. doi: 10.2147/tcrm.1.1.27.53602.

Abstract

INTRODUCTION

The seven-year experience of elective abdominal aortic aneurysm (AAA) repair of a vascular surgical unit in a teaching hospital was reviewed to determine the factors associated with in-hospital mortality.

METHODS

All patients who underwent elective open repair of an AAA between July 1, 1991, and June 30, 1998, were identified using International Classification of Diseases Ninth Revision (ICD-9) codes. Twenty-four variables were selected for investigation by reviewing the published literature and by discussion with local vascular surgeons. Data were obtained by retrospective medical record review. Variables were first analysed by univariate analysis, and those with a p-value up to 0.25 were included in multivariate analysis.

RESULTS

Of the 219 patients reviewed, 8 (3.7%, 95% confidence interval, 1.6%, 7.1%) died during the admission. The mean age of patients was 69.9 years, and 81% of them were male. Univariate analysis found that female sex, renal artery involvement in the aneurysm, and aortic cross-clamp duration of 90 min or greater were significantly associated with mortality. Multivariate analysis found that female sex, use of a bifurcated graft, and performance of an additional procedure at the time of operation were the only variables independently associated with mortality.

DISCUSSION

Use of a bifurcated graft was a significant prognostic variable on logistic regression analysis confirming that the technical difficulty of the operation and the morphology of the aneurysm are important factors in determining mortality. Why women may be at higher risk for death is unclear. This study also highlights that caution is required when interpreting raw audit data.

摘要

简介

本研究回顾了一家教学医院血管外科单元 7 年来行择期腹主动脉瘤(AAA)修复的经验,以确定与院内死亡率相关的因素。

方法

通过国际疾病分类第九版(ICD-9)代码确定 1991 年 7 月 1 日至 1998 年 6 月 30 日间行择期开放修复 AAA 的所有患者。通过回顾已发表的文献并与当地血管外科医生讨论,选择了 24 个变量进行调查。通过回顾病历获得数据。首先通过单变量分析进行变量分析,将 p 值达 0.25 的变量纳入多变量分析。

结果

在 219 例患者中,8 例(3.7%,95%可信区间,1.6%,7.1%)在住院期间死亡。患者的平均年龄为 69.9 岁,81%为男性。单变量分析发现女性、动脉瘤累及肾动脉和主动脉夹闭时间达 90 分钟或以上与死亡率显著相关。多变量分析发现女性、使用分叉式移植物和在手术时进行附加手术是与死亡率独立相关的唯一变量。

讨论

在逻辑回归分析中,使用分叉式移植物是一个显著的预后变量,这证实了手术的技术难度和动脉瘤的形态是决定死亡率的重要因素。为什么女性的死亡风险可能更高尚不清楚。本研究还强调了在解释原始审核数据时需要谨慎。

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