Osório Ana Luiza Alves Rosa, Madruga Claudio Roberto, Desquesnes Marc, Soares Cleber Oliveira, Ribeiro Laura Raquel Rios, Costa Sylvio Celso Gonçalves da
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, 79070-900, Brasil.
Mem Inst Oswaldo Cruz. 2008 Feb;103(1):1-13. doi: 10.1590/s0074-02762008000100001.
The biology, epidemiology, pathogenesis, diagnostic techniques, and history of the introduction of Trypanosoma (Duttonella) vivax in the New World are reviewed. The two main immunological responses of trypanosome-infected animals - antibody production and immunodepression - are discussed in the context of how these responses play a role in disease tolerance or susceptibility. Isolation and purification of T. vivax are briefly discussed. The recent reports of bovine trypanosomiasis diagnosed in cattle on farms located in the Pantanal region of the states of Mato Grosso do Sul and Mato Grosso, Brazil, are also discussed.
本文综述了间日锥虫（杜氏锥虫属）在新大陆的生物学、流行病学、发病机制、诊断技术及引入历史。在锥虫感染动物的两种主要免疫反应——抗体产生和免疫抑制——如何在疾病耐受性或易感性中发挥作用的背景下，对这两种反应进行了讨论。简要讨论了间日锥虫的分离和纯化。还讨论了巴西南马托格罗索州和马托格罗索州潘塔纳尔地区农场牛群中近期诊断出牛锥虫病的报告。
