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抑郁症心理治疗后多发性硬化症患者的抑郁症状、益处发现、乐观主义和积极情绪之间的关系。

Relationships among depressive symptoms, benefit-finding, optimism, and positive affect in multiple sclerosis patients after psychotherapy for depression.

作者信息

Hart Stacey L, Vella Lea, Mohr David C

机构信息

Department of Psychiatry, University of California, San Francisco, CA, USA.

出版信息

Health Psychol. 2008 Mar;27(2):230-8. doi: 10.1037/0278-6133.27.2.230.

Abstract

OBJECTIVE

While many patients with multiple sclerosis (MS) experience psychological problems, such as depression, benefit-finding is commonly reported. Using the Broaden-and-Build Model of positive emotions (Fredrickson, 2001) and the Expectancy-Value Model of optimism (Carver & Scheier, 1998) as two related, yet, distinct conceptual frameworks, this study examined positive affect and optimism as mediators of the relationship between improved depression and enhanced benefit-finding.

DESIGN

MS patients (N=127), who participated in a larger, randomized clinical trial comparing two types of telephone psychotherapy for depression, were assessed at baseline, midtherapy (8 weeks), end of therapy (16 weeks), and 6- and 12-month posttherapy.

MAIN OUTCOME MEASURES

Depression was measured with a telephone administered version of the Hamilton Rating Scale for Depression; Positive Affect was measured with the Positive Affect Subscale from the Positive and Negative Affect Scale; Optimism was measured with the Life Orientation Test-Revised; Benefit-Finding was measured with the revised version of the Stress-Related Growth Scale.

RESULTS

Data were analyzed with multilevel random-effects models, controlling for time since MS diagnosis and type of treatment. Improved depression was associated with increased benefit-finding over time. The relationship between improved depression and benefit-finding was significantly mediated by both increased optimism and increased positive affect.

CONCLUSION

Findings provide support to both theoretical models. Positivity appears to promote benefit-finding in MS.

摘要

目的

虽然许多多发性硬化症(MS)患者会经历心理问题,如抑郁,但也普遍报告了从中发现益处的情况。本研究以积极情绪的拓展与建构模型(弗雷德里克森,2001年)和乐观的期望 - 价值模型(卡弗和谢尔,1998年)作为两个相关但不同的概念框架,考察了积极情感和乐观作为抑郁改善与增强发现益处之间关系的中介变量。

设计

参与一项比较两种电话心理治疗抑郁方法的大型随机临床试验的MS患者(N = 127),在基线、治疗中期(8周)、治疗结束时(16周)以及治疗后6个月和12个月进行评估。

主要结局指标

使用汉密尔顿抑郁评定量表的电话版测量抑郁;使用正负性情绪量表中的积极情感分量表测量积极情感;使用修订版生活取向测试测量乐观;使用修订版压力相关成长量表测量发现益处。

结果

采用多水平随机效应模型分析数据,控制自MS诊断以来的时间和治疗类型。随着时间推移,抑郁改善与发现益处增加相关。抑郁改善与发现益处之间的关系通过乐观增加和积极情感增加均得到显著中介。

结论

研究结果为两种理论模型提供了支持。积极情绪似乎促进了MS患者发现益处。

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