Surrey Community Health, Haslemere, UK.
Behav Cogn Psychother. 2011 Jan;39(1):115-21. doi: 10.1017/S1352465810000536. Epub 2010 Oct 15.
Depression is common in those with MS. The hopelessness theory of depression, emphasizing the role of attributional style, is supported in this population. Cognitive behaviour therapy (CBT) that can affect attributional style can reduce depression in people who have MS.
The present study aimed to consider whether changing attributional style would reduce depression in two people with MS, thereby supporting the importance of this component of CBT with this population.
Two female participants with MS were offered a 5-session intervention designed to alter attributional style. The study followed an ABA design. Attributional style and depressive symptoms were the principal measures considered. Negative life events and MS related stresses were also monitored.
The intervention appeared effective for one of the participants, with predicted changes in attributional style and sizeable reductions in depressive symptoms from pre- to post-treatment that were sustained at 3-month follow-up. Improvement was still evident at 6 months, although with some reduction of effect. The intervention was less successful for the other participant who declined further treatment after three sessions.
Some support for the hopelessness theory of depression was found, indicating its relevance to CBT interventions for those who have MS and depression.
多发性硬化症患者中常见抑郁。在这一人群中，强调归因方式作用的抑郁无望理论得到了支持。能够影响归因方式的认知行为疗法（CBT）可以降低多发性硬化症患者的抑郁程度。
本研究旨在探讨改变归因方式是否会减少两名多发性硬化症患者的抑郁，从而支持 CBT 这一成分对该人群的重要性。
为两名患有多发性硬化症的女性参与者提供了一个旨在改变归因方式的 5 节干预措施。该研究采用 ABA 设计。主要考虑归因方式和抑郁症状。还监测了负面生活事件和多发性硬化症相关压力。
干预措施对其中一名参与者似乎有效，归因方式的预期变化以及治疗前到治疗后的抑郁症状显著减少，在 3 个月的随访中持续存在。在 6 个月时仍有改善，尽管效果有所降低。干预措施对另一名参与者的效果较差，她在三个疗程后拒绝了进一步的治疗。
发现了对抑郁无望理论的一些支持，表明其与针对多发性硬化症和抑郁的 CBT 干预措施相关。
