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黑色物质与康斯坦丁·尼古拉耶维奇·特雷蒂亚科夫

The black stuff and Konstantin Nikolaevich Tretiakoff.

作者信息

Lees Andrew J, Selikhova Marianna, Andrade Luiz Augusto, Duyckaerts Charles

机构信息

The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.

出版信息

Mov Disord. 2008 Apr 30;23(6):777-83. doi: 10.1002/mds.21855.

DOI:10.1002/mds.21855
PMID:18383531
Abstract

Konstantin Tretiakoff's doctoral dissertation "Contribution a l'Etude de L'Anatomie pathologique du Locus Niger de Soemmering avec quelques déductions relatives à la pathogénie des troubles du tonus musculaire et De La Maladie de Parkinson" (A Study of the Pathological anatomy of the locus niger of Soemerring and its relevance to the pathogenesis of changes in muscular tone in Parkinson's disease) published in 1919 earned him a silver medal awarded by the University of Paris but failed to gain him the recognition its importance deserved. Despite belated acknowledgment of the importance of his findings Tretiakoff received little acclaim during his life and there have been no biographical accounts written in English or French. Fifty years after his death it seems appropriate to relate some aspects of his interesting peripatetic life and recognize the continuing relevance of his pioneering research on "the black stuff" to our understanding of Parkinson's disease.

摘要

康斯坦丁·特雷蒂亚科夫1919年发表的博士论文《对索默林黑质的病理解剖学研究以及与肌张力障碍和帕金森病发病机制的一些推论》(《索默林黑质的病理解剖学及其与帕金森病肌肉张力变化发病机制的相关性研究》)为他赢得了巴黎大学颁发的银牌,但未能得到应有的认可。尽管他的发现的重要性得到了迟来的承认,但特雷蒂亚科夫生前很少受到赞誉,也没有用英语或法语撰写的传记。在他去世五十年后,讲述他有趣的漂泊生活的一些方面,并认识到他对“黑质物质”的开创性研究对我们理解帕金森病的持续相关性,似乎是合适的。

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