在携带共同质粒的弗氏柠檬酸杆菌和产酸克雷伯菌临床分离株中检测2型肺炎克雷伯菌碳青霉烯酶（一种碳青霉烯水解酶）
Detection of the Klebsiella pneumoniae carbapenemase type 2 Carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid.
作者信息
Rasheed J Kamile, Biddle James W, Anderson Karen F, Washer Laraine, Chenoweth Carol, Perrin John, Newton Duane W, Patel Jean B
机构信息
Division of Healthcare Quality Promotion, National Center for the Prevention, Detection and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
出版信息
J Clin Microbiol. 2008 Jun;46(6):2066-9. doi: 10.1128/JCM.02038-07. Epub 2008 Apr 2.
Abstract
The Klebsiella pneumoniae carbapenemase (KPC) was detected in carbapenem-resistant isolates of Citrobacter freundii and Klebsiella oxytoca recovered from different patients in a Michigan hospital. Restriction analysis and hybridization with a KPC-specific probe showed the bla(KPC-2) genes of these two genera of the family Enterobacteriaceae are carried on a common plasmid.
摘要
在密歇根一家医院从不同患者身上分离出的弗氏柠檬酸杆菌和产酸克雷伯菌的碳青霉烯耐药菌株中检测到肺炎克雷伯菌碳青霉烯酶（KPC）。限制性分析以及与KPC特异性探针杂交显示，肠杆菌科这两个属的bla(KPC-2)基因存在于同一个质粒上。
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