Romon Isabelle, Jougla Eric, Balkau Beverley, Fagot-Campagna Anne
French Institute for Public Health Surveillance, Institut de Veille Sanitaire (InVS), 12 rue du Val d'Osne, 94415 Saint-Maurice Cedex, France.
Eur J Epidemiol. 2008;23(5):327-34. doi: 10.1007/s10654-008-9235-5.
To describe the burden of diabetes-related mortality in France.
Underlying and multiple causes (all causes listed) of death were extracted from the 2002 French national mortality registry. Death rates were standardized on the age structure of the European population.
Diabetes was reported as the underlying cause of death in 11,177 certificates (2.1%), and as multiple causes in 29,357 certificates (5.3%), giving a ratio (multiple/underlying causes) of 2.6. When diabetes was a multiple cause, the mean age at death was 75 years in men, 81 years in women. The age-standardized mortality rates were 41.0/100,000 in men, 24.6/100,000 in women. The excess mortality observed in men (men/women ratio = 1.7) decreased with age. Geographic differences were observed: higher rates in the North-East, lower rates in the West of the country. In certificates mentioning diabetes, the most frequent cause of death was diseases of the circulatory system (76%). Coronary heart diseases, foot ulcers and renal diseases were more likely to be mentioned in certificates referring to diabetes than in those that did not.
The use of multiple rather than underlying causes of death more than doubled diabetes-related mortality rates. While probably still under-estimated, the burden of diabetes-related mortality corresponds to a high proportion of the total mortality, especially in men. Geographic differences partially reflect disparities in diabetes prevalence. Causes more frequently associated with diabetes include coronary heart disease and complications related to neuropathy and nephropathy.
描述法国糖尿病相关死亡率的负担情况。
从2002年法国国家死亡率登记处提取死亡的根本原因和多种原因(列出所有原因)。死亡率根据欧洲人口的年龄结构进行标准化。
在11177份死亡证明中,糖尿病被报告为根本死因(2.1%),在29357份死亡证明中被报告为多种死因(5.3%),得出比例(多种死因/根本死因)为2.6。当糖尿病作为多种死因时,男性的平均死亡年龄为75岁,女性为81岁。年龄标准化死亡率男性为41.0/10万,女性为24.6/10万。男性中观察到的超额死亡率(男性/女性比例 = 1.7)随年龄下降。观察到地理差异:东北部地区死亡率较高,该国西部地区较低。在提及糖尿病的死亡证明中,最常见的死因是循环系统疾病(76%)。与未提及糖尿病的死亡证明相比,提及糖尿病的死亡证明中更有可能提到冠心病、足部溃疡和肾脏疾病。
使用多种而非根本死因使糖尿病相关死亡率增加了一倍多。虽然可能仍被低估,但糖尿病相关死亡率的负担在总死亡率中占很高比例,尤其是在男性中。地理差异部分反映了糖尿病患病率的差异。与糖尿病更常相关的病因包括冠心病以及与神经病变和肾病相关的并发症。