Savino F, Petrucci E, Nanni Ge
Department of Pediatrics, Regina Margherita Children's Hospital, University of Turin, Turin, Italy.
Acta Paediatr. 2008 Jun;97(6):701-5. doi: 10.1111/j.1651-2227.2008.00750.x. Epub 2008 Apr 7.
Adiponectin, a protein hormone produced by adipocytes, is also found in breast milk, which in turn is implicated in childhood obesity prevention. Although a biological role for adiponectin has not been firmly established, clinical and experimental research indicates that it regulates lipid and glucose metabolism, affects foetal development, and exerts anti-inflammatory and antiatherogenic effects.
This review demonstrates an emerging interest of paediatric research on adiponectin. A better understanding of adiponectin's bioactivity might clarify whether breast milk indeed prevents childhood obesity.
脂联素是一种由脂肪细胞产生的蛋白质激素，在母乳中也有发现，而母乳又与预防儿童肥胖有关。尽管脂联素的生物学作用尚未完全明确，但临床和实验研究表明，它能调节脂质和葡萄糖代谢，影响胎儿发育，并具有抗炎和抗动脉粥样硬化作用。
本综述表明儿科研究对脂联素的兴趣日益浓厚。更好地了解脂联素的生物活性可能会阐明母乳是否真的能预防儿童肥胖。
