Nechaev Sergei, Severinov Konstantin
Laboratory of Molecular Carcinogenesis, NIEHS/NIH, Room D434, 111 Alexander Dr, Research Triangle Park, NC 27709, USA.
Curr Opin Microbiol. 2008 Apr;11(2):186-93. doi: 10.1016/j.mib.2008.02.009. Epub 2008 Apr 8.
Bacteria and their viruses (phages) are locked in an evolutionary contest, with each side producing constantly changing mechanisms of attack and defense that are aimed to increase the odds of survival. As a result, phages play central roles in a great variety of genetic processes and increase the rate of evolutionary change of the bacterial host, which could ultimately work to the benefit of the host in a long run.
细菌及其病毒(噬菌体)处于一场进化竞赛之中,双方都在不断产生变化多样的攻击与防御机制,这些机制旨在提高生存几率。因此,噬菌体在多种基因过程中发挥核心作用,并提高细菌宿主的进化变化速率,从长远来看,这最终可能会造福宿主。