Department of Cardiology, Maastricht University Hospital, Maastricht, the Netherlands.
Neth Heart J. 2008 Apr;16(4):129-33. doi: 10.1007/BF03086131.
Cardiac remodelling is commonly defined as a physiological or pathological state that may occur after conditions such as myocardial infarction, pressure overload, idiopathic dilated cardiomyopathy or volume overload. When training excessively, the heart develops several myocardial adaptations causing a physiological state of cardiac remodelling. These morphological changes depend on the kind of training and are clinically characterised by modifications in cardiac size and shape due to increased load. Several studies have investigated morphological differences in the athlete's heart between athletes performing strength training and athletes performing endurance training. Endurance training is associated with an increased cardiac output and volume load on the left and right ventricles, causing the endurance-trained heart to generate a mild to moderate dilatation of the left ventricle combined with a mild to moderate increase in left ventricular wall thickness. Strength training is characterised by an elevation of both systolic and diastolic blood pressure. This pressure overload causes an increase in left ventricular wall thickness. This may or may not be accompanied by a slight raise in the left ventricular volume. However, the development of an endurancetrained heart and a strength-trained heart should not be considered an absolute concept. Both forms of training cause specific morphological changes in the heart, dependent on the type of sport. (Neth Heart J 2008;16:129-33.).
心脏重构通常被定义为一种生理或病理状态,可能发生在心肌梗死、压力超负荷、特发性扩张型心肌病或容量超负荷等情况下。当过度训练时,心脏会发生几种心肌适应性变化,导致心脏重构的生理状态。这些形态变化取决于训练的类型,临床上表现为由于负荷增加而导致心脏大小和形状的改变。一些研究已经调查了进行力量训练和耐力训练的运动员心脏的形态学差异。耐力训练与左、右心室的心脏输出量和容量负荷增加有关,导致耐力训练的心脏产生轻度至中度的左心室扩张,同时左心室壁厚度轻度至中度增加。力量训练的特点是收缩压和舒张压均升高。这种压力超负荷会导致左心室壁厚度增加。这可能伴有或不伴有左心室容积的轻微升高。然而,耐力训练的心脏和力量训练的心脏的发展不应被视为绝对概念。两种形式的训练都会导致心脏的特定形态变化,这取决于运动的类型。(Neth Heart J 2008;16:129-33)。