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施瓦茨等人所著《射频电磁场(UMTS,1950兆赫)在体外对人成纤维细胞有遗传毒性作用,但对淋巴细胞无此作用》的评论(《国际职业环境健康档案》2008年:doi: 10.1007/s00420-008-0305-5)

Comments on "Radiofrequency electromagnetic fields (UMTS, 1,950 MHz) induce genotoxic effects in vitro in human fibroblasts but not in lymphocytes" by Schwarz et al. (Int Arch Occup Environ Health 2008: doi: 10.1007/s00420-008-0305-5).

作者信息

Lerchl Alexander

机构信息

School of Engineering and Science, Jacobs University Bremen, Bremen, Germany.

出版信息

Int Arch Occup Environ Health. 2009 Jan;82(2):275-8. doi: 10.1007/s00420-008-0323-3. Epub 2008 Apr 24.

Abstract

BACKGROUND

A recent publication by Schwarz et al. describes the effects of exposure of human fibroblast and lymphocytes to radiofrequency-electromagnetic fields at frequencies used for communication with mobile phones. Even at very low specific absorption rates of 0.05 W/kg, thus well below internationally accepted exposure limits, significant effects were seen in fibroblasts whose DNA molecules were damaged as assessed by their comet tail factor (CTF) in the comet assay.

AREAS OF CONCERN

The CTF mean values and the standard deviations of the replicates revealed very low coefficients of variation, ranging from 1.2 to 4.9% (average 2.9%), which are in contrast to much higher variations reported by others. Moreover, inter-individual differences of the CTF values strongly disagree with the previously published data from the same group of researchers.

CONCLUSION

The critical analysis of the data given in the figures and the tables furthermore reveal peculiar miscalculations and statistical oddities which give rise to concern about the origin of the reported data.

摘要

背景

施瓦茨等人最近发表的一篇文章描述了人体成纤维细胞和淋巴细胞暴露于与移动电话通信所用频率的射频电磁场中的影响。即使在非常低的比吸收率0.05瓦/千克的情况下,即远低于国际公认的暴露限值,通过彗星试验中的彗星尾因子(CTF)评估,成纤维细胞的DNA分子仍出现了显著损伤。

关注领域

CTF的平均值和重复样本的标准差显示变异系数非常低,范围在1.2%至4.9%之间(平均2.9%),这与其他人报告的高得多的变异情况形成对比。此外,CTF值的个体间差异与同一组研究人员先前发表的数据严重不符。

结论

对图表中给出的数据进行的批判性分析还揭示了一些特殊的计算错误和统计异常情况,这引发了对所报告数据来源的担忧。

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