幽门螺杆菌与喉癌之间不存在关联。
Lack of association between Helicobacter pylori and laryngeal carcinoma.
作者信息
Masoud Naderpour, Manouchehr Khoshbaten, Najmeh Doostmohammadian, Monireh Halimi
机构信息
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Iran.
出版信息
Asian Pac J Cancer Prev. 2008 Jan-Mar;9(1):81-2.
OBJECTIVE
To survey the role of Helicobacter pylori at the tissue level as a cause of squamous cell carcinoma of the larynx.
DESIGN
A case-control study.
SETTING
In an Otolaryngology Ward at an academic university.
SUBJECTS
Patients with laryngeal cancer as cases and patients with benign laryngeal lesion as controls.
MAIN OUTCOME MEASURE
In all subjects, specimens of laryngeal tissue were examined by rapid urease test while histopathologic examination was achieved to detect H. Pylori.
RESULTS
Totally, 44 patients (42 men and 2 women) with squamous cell carcinoma of larynx and 30 patients (24 men and 6 women) with benign laryngeal lesions (polyp, nodule, granuloma) were studied, none of which were infected with the bacterium.
CONCLUSION
Our results did not show H. Pylori infection among patients with laryngeal cancer (SCC) or benign laryngeal lesions. .
目的
探讨幽门螺杆菌在组织水平上作为喉鳞状细胞癌病因的作用。
设计
病例对照研究。
地点
一所学术性大学的耳鼻喉科病房。
研究对象
喉癌患者作为病例，良性喉部病变患者作为对照。
主要观察指标
对所有研究对象的喉部组织标本进行快速尿素酶试验检测，同时进行组织病理学检查以检测幽门螺杆菌。
结果
共研究了44例喉鳞状细胞癌患者（42例男性和2例女性）和30例良性喉部病变患者（息肉、结节、肉芽肿，24例男性和6例女性），所有患者均未感染该细菌。
结论
我们的研究结果未显示喉癌（鳞状细胞癌）患者或良性喉部病变患者存在幽门螺杆菌感染。
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