Donoso Mantke O, Schädler R, Niedrig M
National Consultant Laboratory for Tick-borne encephalitis and further flaviviruses.
Euro Surveill. 2008 Apr 24;13(17):18848.
The European Network for Diagnostics of "Imported" Viral Diseases (ENIVD) is finalising a project to improve the diagnostic and monitoring of encephalitis viruses in Europe. Part of this study was to analyse the present surveillance situation for tick-borne encephalitis (TBE), which is the most important flavivirus infection of the central nervous system in the European Union (EU) and Russia. A questionnaire was mailed to contact points in all Member States of the EU and three non-EU countries (Norway, Russia and Switzerland) to summarise their TBE surveillance and prevention activities. Information was requested on case definition, type of laboratory tests for TBE diagnostics, investigations regarding tick-transmitted diseases, mapping of endemic foci, vaccination programmes, and recommendations for travellers. The survey gives an overview of the existing epidemiological and laboratory sources of information and the number of TBE cases from 2004 until 2007, but also showed that, in particular, case definitions, diagnostic assays for confirmation, and methods/indicators for mapping risk areas differ widely across the participating countries. The data will help to develop recommendations for the standardisation and quality control or TBE surveillance and diagnostics.
欧洲“输入性”病毒性疾病诊断网络（ENIVD）正在敲定一个项目，以改善欧洲脑炎病毒的诊断和监测。该研究的一部分是分析蜱传脑炎（TBE）目前的监测情况，蜱传脑炎是欧盟（EU）和俄罗斯最重要的中枢神经系统黄病毒感染。向欧盟所有成员国以及三个非欧盟国家（挪威、俄罗斯和瑞士）的联络点邮寄了一份调查问卷，以总结它们的蜱传脑炎监测和预防活动。要求提供有关病例定义、蜱传脑炎诊断的实验室检测类型、蜱传疾病调查、地方性疫源地地图绘制、疫苗接种计划以及给旅行者的建议等信息。该调查概述了2004年至2007年现有的流行病学和实验室信息来源以及蜱传脑炎病例数量，但同时也表明，特别是病例定义、确诊诊断检测方法以及绘制风险区域的方法/指标在参与调查的国家之间差异很大。这些数据将有助于制定蜱传脑炎监测和诊断的标准化及质量控制建议。
