Tubbs R Shane, Loukas Marios, Shoja Mohammadali M, Shokouhi Ghaffar, Oakes W Jerry
Section of Pediatric Neurosurgery, Children's Hospital, University of Alabama at Birmingham, AL 35233, USA.
J Neurosurg. 2008 May;108(5):1038-42. doi: 10.3171/JNS/2008/108/5/1038.
François Magendie lived during a tumultuous period in French history. Although this early medical pioneer made significant contributions to the fields of neuroanatomy, physiology, and pharmacology, little information is found in the non-French literature regarding this significant person in history. Based on this review, one could also consider this trained surgeon as an early pioneer of neurosurgery. For example, he is known to have used Galvanic current to treat various neuralgias, described a technique for extracting cerebrospinal fluid and quantitated and described its characteristics in normal and pathological specimens, and elucidated the functions of the the cranial nerves using vivisection. Additionally, he accurately described the functions of the dorsal and ventral rootlets using vivisection, and realized that the exposed meninges were susceptible to painful stimuli. Our current knowledge is based on the early contributions of scientists such as François Magendie.
弗朗索瓦·马让迪生活在法国历史上一个动荡的时期。尽管这位早期的医学先驱在神经解剖学、生理学和药理学领域做出了重大贡献，但在非法语文献中，关于这位历史上的重要人物的信息却很少。基于这篇综述，人们也可以将这位训练有素的外科医生视为神经外科的早期先驱。例如，众所周知，他曾使用电流治疗各种神经痛，描述了一种提取脑脊液的技术，并对正常和病理标本中的脑脊液进行了定量和描述其特征，还通过活体解剖阐明了颅神经的功能。此外，他通过活体解剖准确描述了背根和腹根的功能，并意识到暴露的脑膜容易受到疼痛刺激。我们目前的知识基于像弗朗索瓦·马让迪这样的科学家的早期贡献。
