Institute for Molecular and Cell Biology, University of Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.
Animals (Basel). 2013 Mar 19;3(1):238-73. doi: 10.3390/ani3010238.
The use of non-human animals in biomedical research has given important contributions to the medical progress achieved in our day, but it has also been a cause of heated public, scientific and philosophical discussion for hundreds of years. This review, with a mainly European outlook, addresses the history of animal use in biomedical research, some of its main protagonists and antagonists, and its effect on society from Antiquity to the present day, while providing a historical context with which to understand how we have arrived at the current paradigm regarding the ethical treatment of animals in research.
在生物医药研究中使用非人类动物为我们当今取得的医学进步做出了重要贡献,但数百年来,它也是公众、科学界和哲学界激烈讨论的一个原因。这篇综述主要从欧洲的角度出发,探讨了动物在生物医药研究中的使用历史、一些主要的支持者和反对者,以及它从古至今对社会的影响,同时提供了一个历史背景,帮助我们理解如何形成当前关于研究中动物伦理待遇的范例。