Gorgun E, Remzi F H, Montague D K, Connor J T, O'Brien K, Loparo B, Fazio V W
Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Colorectal Dis. 2005 Nov;7(6):545-50. doi: 10.1111/j.1463-1318.2005.00895.x.
Restorative Proctocolectomy and Ileal Pouch Anal Anastomosis has become the gold standard surgical therapy for the majority of patients with mucosal ulcerative colitis. However sexual functional disturbances after this procedure can be a concern for patients. Therefore the aim of this study was to determine the outcome of sexual-function related quality of life in male patients undergoing restorative proctocolectomy.
One hundred and twenty-two male patients who underwent restorative proctocolectomy with ileal pouch anal anastomosis between 1995 and 2000 were evaluated by the validated International Index of Erectile Function (IIEF) scoring instrument. This index scale examines sexual function in five categories. These are erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction. The IIEF instrument was administered after surgery and then scores before and after RP/IPAA were evaluated and compared. The significance of age at the time of the surgery, type of surgery, type of anastomotic technique (mucosectomy vs stapled) and septic complications on sexual functional outcome were also investigated.
Mean age at the time of the surgery was 39.9 +/- 11.5 years. The mean follow-up period (time between pouch surgery and IIEF completed) was 3.6 +/- 1.8 years. There was statistically significant improvement in 4 of 5 categories of sexual function (erectile function, sexual desire, intercourse satisfaction, and overall satisfaction) where patients had improved scores after surgery compared to prior to surgery. The mean erectile function score increased pre to post surgery by 2.12 points (P = 0.02), which indicates better sexual results. Anastomotic technique and septic complication did not influence the results, however, older age had a negative impact on results.
Despite some adverse sexual functions, male patients who undergo RP/IPAA for the surgical management of their colitis may preserve or improve their overall sexual functional outcome.
全结直肠切除回肠储袋肛管吻合术已成为大多数黏膜性溃疡性结肠炎患者的金标准外科治疗方法。然而,该手术后的性功能障碍可能是患者关注的问题。因此,本研究的目的是确定接受全结直肠切除回肠储袋肛管吻合术的男性患者性功能相关生活质量的结果。
采用经过验证的国际勃起功能指数(IIEF)评分工具,对1995年至2000年间接受全结直肠切除回肠储袋肛管吻合术的122例男性患者进行评估。该指数量表从五个类别检查性功能。分别是勃起功能、性高潮功能、性欲、性交满意度和总体满意度。IIEF工具在手术后使用,然后评估并比较全结直肠切除/回肠储袋肛管吻合术前后的评分。还研究了手术时的年龄、手术类型、吻合技术类型(黏膜切除术与吻合器吻合术)和感染并发症对性功能结果的影响。
手术时的平均年龄为39.9±11.5岁。平均随访期(储袋手术与完成IIEF之间的时间)为3.6±1.8年。5类性功能中的4类(勃起功能、性欲、性交满意度和总体满意度)有统计学意义的改善,与手术前相比,患者手术后得分有所提高。勃起功能平均得分从术前到术后增加了2.12分(P = 0.02),这表明性功能结果更好。吻合技术和感染并发症并未影响结果,然而,年龄较大对结果有负面影响。
尽管存在一些不良性功能,但因结肠炎接受全结直肠切除/回肠储袋肛管吻合术的男性患者可能会保持或改善其总体性功能结果。