Olawoye Olusola, Ashaye Adelina A, Sarimiye Tarela F
Department of Ophthalmology, University of Ibadan College of Medicine, Ibadan, Oyo, Nigeria.
Department of Ophthalmology, University College Hospital, Ibadan, Oyo, Nigeria.
Ghana Med J. 2017 Dec;51(4):175-180.
To report the safety and efficacy of Argon Laser Trabeculoplasty (ALT) in reducing intraocular pressure (IOP).
This was a retrospective study performed on 25 eyes of 25 patients.
Consecutive patients who met the inclusion criteria for ALT were recruited from the ophthalmic clinic of the University College Hospital Ibadan, Nigeria and followed up for a minimum period of six months. Two criteria were used to define successful response. Criterion 1 was defined as IOP reduction of 3mmHg or more without additional intervention while criterion 2 was IOP reduction of 20% or more from the pretreatment IOP.
Data was analyzed using SPSS version 16. Frequencies and means were generated to observe patterns of variable distribution among the patients. P value < 0.05 was considered significant.
The mean pretreatment IOP was 19.9 ±3.1mmHg, (range of 16 to 26 mmHg). Mean post treatment IOP at 6 months was 14.9 ±2.2 mmHg, (range of 11 to 19 mmHg). Mean IOP reduction at one year was 4.6 mmHg, representing a 22.3% drop. There was a statistically significant greater IOP reduction in eyes (P<0.001) with higher pretreatment IOP. Based on criterion 1 and 2, 84.0% of the patients had successful outcome at six months while at one year, 76.9% were successful based on criterion one.
To the best of our knowledge, this is the first study to report the efficacy of ALT in Nigerians. ALT is safe and effective in reducing IOP in Nigerians.
ALT is safe and effective in reducing intraocular pressure in this population of Nigerians.
The present study did not receive any funds.
报告氩激光小梁成形术（ALT）降低眼压（IOP）的安全性和有效性。
这是一项对25例患者的25只眼进行的回顾性研究。
从尼日利亚伊巴丹大学学院医院眼科门诊招募符合ALT纳入标准的连续患者，并进行至少六个月的随访。采用两个标准来定义成功的反应。标准1定义为眼压降低3mmHg或更多且无需额外干预，而标准2定义为眼压较治疗前降低20%或更多。
使用SPSS 16版对数据进行分析。生成频率和均值以观察患者中变量分布的模式。P值<0.05被认为具有显著性。
治疗前平均眼压为19.9±3.1mmHg（范围为16至26mmHg）。6个月时治疗后平均眼压为14.9±2.2mmHg（范围为11至19mmHg）。一年时平均眼压降低4.6mmHg，降幅为22.3%。治疗前眼压较高的眼眼压降低在统计学上更显著（P<0.001）。根据标准1和2，84.0%的患者在六个月时有成功的结果，而在一年时，基于标准一，76.9%的患者成功。
据我们所知，这是第一项报告ALT对尼日利亚人有效性的研究。ALT在降低尼日利亚人的眼压方面是安全有效的。
ALT在降低这群尼日利亚人的眼压方面是安全有效的。
本研究未获得任何资金。
