Rapoport E M, Kurmyshkina O V, Bovin N V
Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Biochemistry (Mosc). 2008 Apr;73(4):393-405. doi: 10.1134/s0006297908040032.
Galectins are a family of beta-galactoside binding lectins, homological by a sequence of the carbohydrate-binding site. In this review literature data about structure and carbohydrate specificity of galectins are discussed. The role of galectins in the regulation of cell adhesion in immune response, inflammation, and cancer progression is considered.
半乳糖凝集素是一类β-半乳糖苷结合凝集素，通过碳水化合物结合位点的序列具有同源性。在这篇综述中，讨论了有关半乳糖凝集素结构和碳水化合物特异性的文献数据。还探讨了半乳糖凝集素在免疫反应、炎症和癌症进展中细胞黏附调节中的作用。
