像母亲一样，像微生物一样：人乳寡糖介导的微生物组共生。
Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis.
机构信息
Department of Chemistry, Vanderbilt University, 7330 Stevenson Center Lane, Nashville, Tennessee, U.S.A.
出版信息
Biochem Soc Trans. 2020 Jun 30;48(3):1139-1151. doi: 10.1042/BST20191144.
Abstract
Starting shortly after parturition, and continuing throughout our lifetime, the gut microbiota coevolves with our metabolic and neurological programming. This symbiosis is regulated by a complex interplay between the host and environmental factors, including diet and lifestyle. Not surprisingly, the development of this microbial community is of critical importance to health and wellness. In this targeted review, we examine the gut microbiome from birth to 2 years of age to characterize the role human milk oligosaccharides play in early formation of microbial flora.
摘要
从分娩后不久开始，并持续贯穿我们的一生，肠道微生物群与我们的代谢和神经编程共同进化。这种共生关系受到宿主和环境因素（包括饮食和生活方式）之间复杂相互作用的调节。毫不奇怪，这个微生物群落的发展对健康和幸福至关重要。在本次有针对性的综述中，我们研究了从出生到 2 岁的肠道微生物组，以描述人乳寡糖在微生物菌群早期形成中的作用。
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