Yamaguchi Miyuki, Iwakiri Ryuichi, Yamaguchi Kanako, Mizuta Toshihiko, Shimoda Ryo, Sakata Yasuhisa, Hisatomi Akitaka, Mizuguchi Masanobu, Sato Seiji, Miyazaki Kohji, Fujimoto Kazuma
Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
J Gastroenterol. 2008;43(4):265-9. doi: 10.1007/s00535-007-2157-2. Epub 2008 May 6.
Bleeding and stenosis are serious complications of reflux esophagitis, although few studies have been performed in Japan regarding these complications. This study aimed to indicate the characteristics of reflux esophagitis observed during emergency endoscopic examination in Japan.
All subjects who had emergency endoscopic examination performed between 1990 and 2004 at Saga Medical School Hospital were evaluated. Patients with endoscopic reflux esophagitis were evaluated with a retrospective patient chart review.
A total of 1621 subjects underwent emergency endoscopy; 1420 of the endoscopies were because of hematemesis or melena. Endoscopic examination revealed that 19 cases with bleeding were caused by reflux esophagitis (19/1621, 1.2%). The 19 patients with bleeding and the four patients with stenosis (0.2%) had emergency endoscopy performed for complications of reflux esophagitis. The Los Angeles classification of these 23 cases showed that most were severe esophagitis (grade A, 0; B, 2; C, 8; and D, 13). The frequency of comorbidity with diabetes mellitus and collagen disease and the proportion of heavy drinkers were higher in patients who received emergency endoscopy because of reflux esophagitis than in those diagnosed with reflux esophagitis but who received emergency endoscopy because of other diseases.
Relatively small numbers of patients with reflux esophagitis undergo emergency endoscopy in Japan, and most such patients have underlying diseases, including diabetes mellitus and collagen disease. This finding is supported by a previous report that severe esophagitis is not common in Japan.
出血和狭窄是反流性食管炎的严重并发症,尽管在日本针对这些并发症开展的研究较少。本研究旨在指出在日本急诊内镜检查中观察到的反流性食管炎的特征。
对1990年至2004年期间在佐贺医科大学医院接受急诊内镜检查的所有受试者进行评估。对内镜诊断为反流性食管炎的患者进行回顾性病历审查。
共有1621名受试者接受了急诊内镜检查;其中1420例是因呕血或黑便进行检查。内镜检查发现,19例出血是由反流性食管炎引起的(19/1621,1.2%)。这19例出血患者和4例狭窄患者(0.2%)因反流性食管炎并发症接受了急诊内镜检查。这23例患者的洛杉矶分类显示,大多数为重度食管炎(A级,0例;B级,2例;C级,8例;D级,13例)。因反流性食管炎接受急诊内镜检查的患者中,糖尿病和胶原病的合并症发生率以及重度饮酒者的比例高于因其他疾病诊断为反流性食管炎但接受急诊内镜检查的患者。
在日本,因反流性食管炎接受急诊内镜检查的患者相对较少,且大多数此类患者患有包括糖尿病和胶原病在内的基础疾病。这一发现得到了先前一份报告的支持,该报告指出重度食管炎在日本并不常见。