Kolappaswamy Krishnan, Shipley Steven T, Tatarov Ivan I, DeTolla Louis J
Program of Comparative Medicine, Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
J Am Assoc Lab Anim Sci. 2008 May;47(3):64-7.
We describe a case of methicillin-resistant Staphylococcus non-aureus infection in a rhesus macaque (Macaca mulatta). The nonhuman primate described was part of a research project that involved whole-body gamma irradiation and subsequently developed acute generalized dermatitis with skin dryness, peeling, and erythema around the eyes. After initial evaluation, which included microbiologic culture and 6 d of medical treatment, the animal was euthanized due to concern regarding a possible outbreak of infectious or zoonotic disease. On the basis of skin culture, diagnosis of methicillin-resistant Staphylococcus non-aureus was confirmed. This report underscores the importance of the occupational risk of methicillin-resistant Staphylococcus non-aureus to research and animal care staff in a research animal facility setting.
我们描述了一例恒河猴（猕猴）耐甲氧西林非金黄色葡萄球菌感染病例。所述非人灵长类动物是一个涉及全身伽马辐射的研究项目的一部分，随后出现了急性全身性皮炎，伴有皮肤干燥、脱皮以及眼部周围红斑。经过初步评估，包括微生物培养和6天的药物治疗后，由于担心可能爆发传染病或人畜共患病，该动物被实施安乐死。根据皮肤培养结果，确诊为耐甲氧西林非金黄色葡萄球菌感染。本报告强调了在研究动物设施环境中，耐甲氧西林非金黄色葡萄球菌对研究人员和动物护理人员构成的职业风险的重要性。
