Zallek Sarah Nath, Redenius Rachel, Fisk Holly, Murphy Carli, O'Neill Erin
Illinois Neurological Institute Sleep Center, 530 N.E. Glen OakAve., Peoria, IL 61637, USA.
J Clin Sleep Med. 2008 Apr 15;4(2):143-8.
A single subjective question may be an effective screening tool for excessive daytime sleepiness. This study sought to determine whether the following single question about sleepiness can measure subjective sleepiness comparably to the Epworth Sleepiness Scale (ESS): "Please measure your sleepiness on a typical day: (0 = none, 10 is highest)." The relationship between this question and objective sleepiness as measured by the MSLT was also evaluated.
303 subjects completed a sleep questionnaire, MSLT, and ESS within 2 months. ROC (receiver-operator characteristic) curves and contingency tables using Fisher's exact test were made using GraphPad Prism software.
ESS and SS scores showed a significant association at all SS score cut-points. ESS and MSL showed significant associations only at ESS scores 11, 12, and 18. SS scores were significantly related to the MSL only in non-sleep apneics at SS scores 2, 5, 6, and 8, and in sleep apneics at SS score 9. ROC analysis showed the SS could distinguish subjects with an ESS > or = 11 from those with an ESS < 11 (area = 0.71, p < 0.0001).
Neither the SS nor the ESS substitutes for the MSLT, which measures objective sleepiness and is not an appropriate screening tool. SS scores < or = 2 and > or = 9 reliably predict normal and abnormal ESS scores respectively. Since the ESS is not commonly used in non-sleep specialized practices, the SS may serve as a useful screening tool for patients with disorders of sleepiness.
单个主观问题可能是一种有效的日间过度嗜睡筛查工具。本研究旨在确定以下关于嗜睡的单个问题能否与爱泼沃斯嗜睡量表(ESS)一样有效测量主观嗜睡程度:“请评估您在平常一天中的嗜睡程度:(0 = 无,10为最高)。” 同时还评估了该问题与通过多导睡眠图监测(MSLT)测量的客观嗜睡程度之间的关系。
303名受试者在2个月内完成了一份睡眠问卷、多导睡眠图监测和爱泼沃斯嗜睡量表评估。使用GraphPad Prism软件制作了采用费舍尔精确检验的ROC(受试者工作特征)曲线和列联表。
在所有的SS评分切点处,ESS和SS评分均显示出显著相关性。仅在ESS评分为11、12和18时,ESS与MSL显示出显著相关性。仅在SS评分为2、5、6和8的非睡眠呼吸暂停患者以及SS评分为9的睡眠呼吸暂停患者中,SS评分与MSL显著相关。ROC分析表明,SS能够区分ESS≥11的受试者与ESS<11的受试者(曲线下面积 = 0.71,p<0.0001)。
无论是SS还是ESS都不能替代多导睡眠图监测,多导睡眠图监测用于测量客观嗜睡程度,并非合适的筛查工具。SS评分≤2和≥9分别可靠地预测了正常和异常的ESS评分。由于ESS在非睡眠专科实践中并不常用,SS可能是一种用于嗜睡症患者的有用筛查工具。