Yu Zheya Jenny, Weller Ronald A, Sandidge Kendra, Weller Elizabeth B
Children's Hospital of Philadelphia, 3440 Market Street, Philadelphia, PA 19104, USA.
Curr Psychiatry Rep. 2008 Apr;10(2):116-22. doi: 10.1007/s11920-008-0021-6.
Vagus nerve stimulation (VNS) therapy has been approved by the US Food and Drug Administration for treatment-resistant depression in patients 18 years of age and older and for intractable epilepsy. Long-term studies suggest VNS has an antidepressant effect in adults. This paper reviews the available clinical data for VNS therapy. Its potential application for treatment-resistant depression in adolescents and children is also discussed.
迷走神经刺激(VNS)疗法已获美国食品药品监督管理局批准,用于治疗18岁及以上患者的难治性抑郁症和顽固性癫痫。长期研究表明,VNS对成年人有抗抑郁作用。本文回顾了VNS疗法的现有临床数据。还讨论了其在青少年和儿童难治性抑郁症治疗中的潜在应用。