Tsuboi Hiromi
Department of Dermatology, National Hospital Organization, Yokohama Medical Center, Kanagawa, Japan.
J Dermatol. 2008 May;35(5):289-92. doi: 10.1111/j.1346-8138.2008.00468.x.
It is occasionally difficult to distinguish between Behcet's disease (BD) and pyoderma gangrenous (PG). Our case showed ulcers of the oral, vaginal and perineal areas, and in the ileum, thus resulting in our initial diagnosis of BD. However, the patient showed a continued leukopenia, and she was subsequently diagnosed by bone marrow biopsy as having a myelodysplastic syndrome, which will sometimes accompany PG. In addition, following a hysterectomy, the ulcers of the stump in the vagina and the perineum showed the characteristic findings of a PG-like destructive ulceration. Based on these findings, we finally diagnosed our case to have PG.
白塞病（BD）和坏疽性脓皮病（PG）有时很难区分。我们的病例表现为口腔、阴道和会阴区域以及回肠出现溃疡，因此我们最初诊断为BD。然而，患者持续白细胞减少，随后通过骨髓活检诊断为骨髓增生异常综合征，该综合征有时会伴有PG。此外，子宫切除术后，阴道和会阴残端的溃疡表现出类似PG的破坏性溃疡的特征性表现。基于这些发现，我们最终诊断该病例为PG。
