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有记忆问题的受试者中加速遗忘。一种新形式的轻度认知障碍？

Accelerated forgetting in subjects with memory complaints. A new form of Mild Cognitive Impairment?

作者信息

Manes Facundo, Serrano Cecilia, Calcagno María L, Cardozo Julian, Hodges John

机构信息

Institute of Cognitive Neurology (INECO), Castex 3293 (1425), Buenos Aires, Argentina.

出版信息

J Neurol. 2008 Jul;255(7):1067-70. doi: 10.1007/s00415-008-0850-6. Epub 2008 May 23.

DOI:10.1007/s00415-008-0850-6
PMID:18484236
Abstract

A study was carried out to investigate accelerated forgetting of new verbal and visual material in participants complaining of memory loss, individuals with Mild Cognitive Impairment(MCI) and controls. All groups were evaluated with a standard neuropsychological battery and two tests of delayed recall 6 weeks apart for the experimental tasks.Individuals with memory complaints,but not MCI, performed normally compared to controls on immediate and 30 minute recall,but showed a striking impairment in verbal and visual memory after 6 weeks. Accelerated forgetting may go undetected on standard neuropsychological evaluation in some patients complaining of memory problems.

摘要

一项研究旨在调查主诉记忆丧失的参与者、轻度认知障碍（MCI）患者和对照组中对新的言语和视觉材料的加速遗忘情况。所有组均接受标准神经心理学成套测验评估，并对实验任务进行两项间隔6周的延迟回忆测试。有记忆主诉但无MCI的个体在即时回忆和30分钟回忆时与对照组相比表现正常，但在6周后言语和视觉记忆出现显著损害。在一些主诉记忆问题的患者中，加速遗忘在标准神经心理学评估中可能未被发现。

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