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既往乳腺癌患者对疾病复发的担忧:一项验证与患病率研究

Concerns of former breast cancer patients about disease recurrence: a validation and prevalence study.

作者信息

van den Beuken-van Everdingen Marieke H J, Peters Madelon L, de Rijke Janneke M, Schouten Harry C, van Kleef Maarten, Patijn Jacob

机构信息

Pain Management and Research Center, University Hospital Maastricht, Maastricht, The Netherlands.

出版信息

Psychooncology. 2008 Nov;17(11):1137-45. doi: 10.1002/pon.1340.

DOI:10.1002/pon.1340
PMID:18484568
Abstract

OBJECTIVE

The present study has three aims: first, to evaluate the psychometric properties of the Dutch version of the CARS (CARS-DLV). Second, to measure the prevalence of concerns about disease recurrence in former breast cancer patients and identify potential predictors and third, to establish how fear of recurrence was effecting quality of life.

METHODS

A prospective study was carried out on breast cancer patients (n=136) who had undergone curative treatment. Eligible patients completed an extensive questionnaire consisting of the CARS (fear of recurrence), HADS (anxiety and depression), BPI (pain), RAND (quality of life), LOT (optimism) and the PCS (catastrophizing).

RESULTS

This study confirmed the good internal consistency, test-retest stability and construct validity of the CARS (Dutch Language version). Moderate to high levels of fear of disease recurrence were found in 56% of 136 breast cancer survivors. Worries about health and death were the most prominent. Pain was a strong predictor of overall fear and of fear on the four sub domains of the CARS. The prevalence of fear decreased significantly with age. Education level, living arrangements and time since the last treatment did not predict the prevalence of overall fear. Fear of recurrence was negatively correlated with quality of life.

CONCLUSION

The CARS-DLV proved to be a valuable instrument to measure women's' concerns about breast cancer recurrence. More than half of former breast cancer patients indicated moderate to severe concerns about disease recurrence. Health and death worries were the most prominent. The levels of worry were independent of the time since diagnosis.

摘要

目的

本研究有三个目标:第一,评估荷兰语版癌症复发恐惧量表(CARS-DLV)的心理测量特性。第二,测量既往乳腺癌患者对疾病复发的担忧程度,并确定潜在的预测因素。第三,确定复发恐惧如何影响生活质量。

方法

对接受了根治性治疗的乳腺癌患者(n = 136)进行了一项前瞻性研究。符合条件的患者完成了一份详尽的问卷,问卷包括癌症复发恐惧量表(恐惧复发)、医院焦虑抑郁量表(焦虑和抑郁)、简明疼痛量表(疼痛)、兰德健康调查简表(生活质量)、生活取向测试(乐观)和灾难化量表(灾难化)。

结果

本研究证实了癌症复发恐惧量表(荷兰语版)具有良好的内部一致性、重测稳定性和结构效度。在136名乳腺癌幸存者中,56%的人存在中度至高度的疾病复发恐惧。对健康和死亡的担忧最为突出。疼痛是总体恐惧以及癌症复发恐惧量表四个子领域恐惧的有力预测因素。恐惧程度随年龄显著降低。教育水平、生活安排和上次治疗后的时间并不能预测总体恐惧的发生率。复发恐惧与生活质量呈负相关。

结论

癌症复发恐惧量表荷兰语版被证明是测量女性对乳腺癌复发担忧的一个有价值的工具。超过一半的既往乳腺癌患者表示对疾病复发存在中度至重度担忧。对健康和死亡的担忧最为突出。担忧程度与确诊后的时间无关。

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