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家庭干预及其对普通人群中青少年饮酒行为的影响:一项随机对照试验的荟萃分析。

Family interventions and their effect on adolescent alcohol use in general populations; a meta-analysis of randomized controlled trials.

作者信息

Smit Evelien, Verdurmen Jacqueline, Monshouwer Karin, Smit Filip

机构信息

Trimbos Institute (Netherlands Institute of Mental Health and Addiction), 3500 AS Utrecht, The Netherlands.

出版信息

Drug Alcohol Depend. 2008 Oct 1;97(3):195-206. doi: 10.1016/j.drugalcdep.2008.03.032. Epub 2008 May 15.

Abstract

AIMS

In order to quantify the effectiveness of family interventions in reducing adolescent drinking, we conducted a meta-analysis of randomized controlled trials.

METHODS

We searched the Cochrane Database of Systematic Reviews, ERIC (Educational Research Information Center), Medline and PsycInfo for studies published between 1995 and September 2006. Summary estimates (OR and Cohen's d) were derived from the difference in changed alcohol consumption between family intervention and control group. Random effect models were used to estimate the overall effect and heterogeneity among studies. Eighteen papers describing nine independent trials were eligible for inclusion in this meta-analysis.

RESULTS

The overall effect of family interventions in reducing alcohol initiation (OR: 0.71; 95% CI: 0.54, 0.94) and frequency of alcohol use (d: -0.25; 95% CI: -0.37, -0.12) show the success of these programs. There was heterogeneity between studies reporting on alcohol initiation (p-heterogeneity: <0.001; I2: 78.6%). Yet, the most successful interventions continued to be effective in reducing alcohol initiation even at 48 months follow-up (pooled estimate (OR): 0.53; 95% CI: 0.38, 0.75).

CONCLUSION

The results from this meta-analysis suggest that the overall effect of family interventions on adolescent alcohol use is small, yet consistent and effective even at 48 months.

摘要

目的

为了量化家庭干预在减少青少年饮酒方面的效果,我们对随机对照试验进行了一项荟萃分析。

方法

我们检索了考克兰系统评价数据库、教育资源信息中心(ERIC)、医学期刊数据库(Medline)和心理学文摘数据库(PsycInfo),以查找1995年至2006年9月期间发表的研究。汇总估计值(比值比(OR)和科恩d值)来自家庭干预组和对照组在酒精摄入量变化方面的差异。采用随机效应模型来估计研究之间的总体效应和异质性。18篇描述9项独立试验的论文符合纳入该荟萃分析的条件。

结果

家庭干预在减少饮酒起始(OR:0.71;95%置信区间:0.54,0.94)和饮酒频率(d:-0.25;95%置信区间:-0.37,-0.12)方面的总体效果表明这些项目取得了成功。在报告饮酒起始情况的研究之间存在异质性(p异质性:<0.001;I²:78.6%)。然而,即使在48个月的随访中,最成功的干预措施在减少饮酒起始方面仍然有效(合并估计值(OR):0.53;95%置信区间:0.38,0.75)。

结论

该荟萃分析的结果表明,家庭干预对青少年饮酒的总体影响较小,但即使在48个月时也是一致且有效的。

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