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脾脓肿:三例报告

Abscesses of the spleen: report of three cases.

作者信息

Fotiadis Constantin, Lavranos Giagkos, Patapis Pavlos, Karatzas Gabriel

机构信息

3rd Department of Surgery, Attikon University Hospital, Piraeus 18538, Greece.

出版信息

World J Gastroenterol. 2008 May 21;14(19):3088-91. doi: 10.3748/wjg.14.3088.

Abstract

Abscess of the spleen is a rare discovery, with about 600 cases in the international literature so far. Although it may have various causes, it is most usually associated with trauma and infections of the spleen. The latter are more common in the presence of a different primary site of infection, especially endocarditis or in cases of ischemic infarcts that are secondarily infected. Moreover, immunosuppression is a major risk factor. Clinical examination usually reveals a combination of fever, left-upper-quadrant abdominal pain and vomiting. Laboratory findings are not constant. Imaging is a necessary tool for establishing the diagnosis, with a choice between ultrasound and computed tomography. Treatment includes conservative measures, and surgical intervention. In children and in cases of solitary abscesses with a thick wall, percutaneous catheter drainage may be attempted. Otherwise, splenectomy is the preferred approach in most centers. Here, we present three cases of splenic abscess. In all three, splenectomy was performed, followed by rapid clinical improvement. These cases emphasize that current understanding of spleen abscess etiology is still limited, and a study for additional risk factors may be necessary.

摘要

脾脓肿是一种罕见的病症,迄今为止国际文献中报道的病例约有600例。尽管其病因可能多种多样,但最常见的是与脾脏创伤和感染有关。后者在存在不同的原发性感染部位时更为常见,尤其是心内膜炎,或在继发感染的缺血性梗死病例中。此外,免疫抑制是一个主要危险因素。临床检查通常会发现发热、左上腹腹痛和呕吐等症状。实验室检查结果并不固定。影像学检查是确诊的必要手段,可选择超声或计算机断层扫描。治疗方法包括保守治疗和手术干预。对于儿童以及壁厚的孤立性脓肿病例,可尝试经皮导管引流。否则,在大多数中心,脾切除术是首选方法。在此,我们介绍三例脾脓肿病例。在所有这三例中,均实施了脾切除术,随后临床症状迅速改善。这些病例强调,目前对脾脓肿病因的认识仍然有限,可能有必要开展关于其他危险因素的研究。

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