来自内生真菌木层孔菌属PSU-D14的代谢产物。
Metabolites from the endophytic fungus Xylaria sp. PSU-D14.
作者信息
Pongcharoen Wipapan, Rukachaisirikul Vatcharin, Phongpaichit Souwalak, Kühn Till, Pelzing Matthias, Sakayaroj Jariya, Taylor Walter C
机构信息
Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla 90112, Thailand.
出版信息
Phytochemistry. 2008 Jun;69(9):1900-2. doi: 10.1016/j.phytochem.2008.04.003. Epub 2008 May 19.
Glucoside derivatives, xylarosides A (1) and B (2), were isolated from the broth extract of the endophytic fungus Xylaria sp. PSU-D14 along with two known compounds, sordaricin (3) and 2,3-dihydro-5-hydroxy-2-methyl-4H-1-benzopyran-4-one (4). The structures were assigned by spectroscopic methods. Sordaricin (3), one of the known metabolites, exhibited moderate antifungal activity against Candida albicans ATCC90028 with a MIC value of 32 microg/ml.
从内生真菌木层孔菌属PSU-D14的发酵液提取物中分离得到了葡萄糖苷衍生物木糖糖苷A（1）和B（2），以及两种已知化合物索德菌素（3）和2,3-二氢-5-羟基-2-甲基-4H-1-苯并吡喃-4-酮（4）。通过光谱方法确定了其结构。已知代谢产物之一索德菌素（3）对白色念珠菌ATCC90028表现出中等抗真菌活性，MIC值为32微克/毫升。
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