Devkota Krishna P, Lenta Bruno N, Fokou Patrice A, Sewald Norbert
Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, 33501 Bielefeld, Germany.
Nat Prod Rep. 2008 Jun;25(3):612-30. doi: 10.1039/b704958g. Epub 2008 Apr 9.
The plants of the family Buxaceae are widely used in traditional medicine and constitute rich sources of terpenoidal alkaloids. Compounds of this family have been the subject of numerous chemical and pharmacological studies over past decades because of their interesting biological activities such as cholinesterase inhibition, as well as antibacterial and antileishmanial activities. The chemical and biological properties of these alkaloids, including data relevant to straightforward structure determination and information on biosynthesis, are highlighted in this review, with 144 references being cited.
黄杨科植物在传统医学中广泛应用，是萜类生物碱的丰富来源。由于该科化合物具有诸如胆碱酯酶抑制以及抗菌和抗利什曼原虫活性等有趣的生物活性，在过去几十年里一直是众多化学和药理学研究的对象。本综述着重介绍了这些生物碱的化学和生物学特性，包括与直接结构测定相关的数据以及生物合成信息，并引用了144篇参考文献。
