Magremanne M, Vervaet C
Service de stomatologie et chirurgie maxillo-faciale, CIU, hôpital Ambroise-Paré, université Libre de Bruxelles, 2, boulevard Kennedy, 7000 Mons, Belgique.
Rev Stomatol Chir Maxillofac. 2008 Jun;109(3):175-7. doi: 10.1016/j.stomax.2008.02.003. Epub 2008 May 27.
The oral melanoma (OM) account for 1% of all melanomas. The prognosis is poor despite an adequate locoregional control of the disease.
A 45-year-old woman presented with submandibular lymph nodes, having metastised from a melanoma. Oral cavity examination revealed a pigmented lesion of the gingiva in front of tooth 12, with satellite spots. Surgical treatment, radiotherapy, chemotherapy, and immunotherapy failed and the patient died 16 months after diagnosis.
Oral melanomas have a poor prognosis probably because they are generally detected late. The most common sites for oral melanomas are the palate and maxillary gingiva. About 30% of OM is preceded by areas of oral pigmentation for several months or years. The prognosis is poor with a 5% to 20% five-year survival rate.
口腔黑色素瘤（OM）占所有黑色素瘤的1%。尽管对该疾病进行了充分的局部区域控制，但其预后仍然很差。
一名45岁女性出现下颌下淋巴结转移，原发于黑色素瘤。口腔检查发现12号牙前方牙龈有色素沉着病变，并伴有卫星灶。手术治疗、放疗、化疗和免疫治疗均失败，患者在诊断后16个月死亡。
口腔黑色素瘤预后较差，可能是因为它们通常发现较晚。口腔黑色素瘤最常见的部位是腭部和上颌牙龈。约30%的口腔黑色素瘤在出现前数月或数年有口腔色素沉着区域。其预后较差，五年生存率为5%至20%。
