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口腔原发性恶性黑色素瘤。1例罕见病例报告。

Primary malignant melanoma of the oral cavity. Report of an unusual case.

作者信息

Dimitrakopoulos I, Lazaridis N, Skordalaki A

机构信息

University Clinic of Oral and Maxillofacial Surgery, G. Papanikolaou General Hospital, Aristotle University of Thessaloniki, Greece.

出版信息

Aust Dent J. 1998 Dec;43(6):379-81.

PMID:9973703
Abstract

Primary malignant melanoma is only rarely found in the oral cavity (estimated at between 0.2 and 8 per cent of all melanomas) and occurs approximately four times more frequently in the oral mucosa of the upper jaw, usually on the palate or alveolar gingivae. A case is reported of a malignant melanoma in the mouth of a 74 year old male, which was originally diagnosed as reactive denture hyperplasia caused by a ill-fitting upper denture. Correction of the denture fault failed to stop the growth of the mass, which was therefore removed surgically. Histological examination revealed a melanin-producing tumour. A partial maxillectomy was performed and there was no evidence of recurrence over a three year follow-up period.

摘要

原发性恶性黑色素瘤在口腔中极为罕见(估计占所有黑色素瘤的0.2%至8%),在上颌口腔黏膜中的发生率约为其他部位的四倍,通常发生于腭部或牙槽龈。本文报告一例74岁男性口腔恶性黑色素瘤病例,该病例最初被诊断为由不合适的上假牙引起的反应性假牙增生。矫正假牙缺陷未能阻止肿物生长,因此进行了手术切除。组织学检查显示为产生黑色素的肿瘤。实施了部分上颌骨切除术,在三年的随访期内未发现复发迹象。

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