Ohno Akira, Kato Naoyuki, Sakamoto Ryota, Kimura Soichiro, Yamaguchi Keizo
Department of Microbiology and Infectious Disease, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-Ku, Tokyo 143-8540, Japan.
Appl Environ Microbiol. 2008 Jul;74(14):4585-8. doi: 10.1128/AEM.00083-08. Epub 2008 May 23.
We analyzed the effects of temperature on the interaction of Legionella pneumophila with Acanthamoeba castellanii. At <20 degrees C, overexpression of type 1 metacaspase, a stimulator of A. castellanii encystation, was associated with a reduced number of bacteria within amoeba. At low temperatures, A. castellanii seems to eliminate L. pneumophila by encystation and digestion.
我们分析了温度对嗜肺军团菌与卡氏棘阿米巴相互作用的影响。在低于20摄氏度时,1型metacaspase(卡氏棘阿米巴包囊化的刺激因子)的过表达与阿米巴内细菌数量减少有关。在低温下,卡氏棘阿米巴似乎通过包囊化和消化来清除嗜肺军团菌。