Turan Hale, Serefhanoglu Kivanc, Torun Ayse Nur, Kulaksizoglu Sevsen, Kulaksizoglu Mustafa, Pamuk Baris, Arslan Hande
Infectious Disease and Clinical Microbiology Department, Faculty of Medicine, Baskent University, Ankara, Turkey.
Jpn J Infect Dis. 2008 May;61(3):236-8.
Urinary tract infection is a serious problem in diabetic patients, and asymptomatic bacteriuria (ASB) in these patients is a risk factor for pyelonephritis and renal dysfunction. In the present study, we investigated the relationships between age, body mass index, duration of diabetes, HbA1c level, glucosuria, glomerular filtration rate and microalbuminuria in type 2 diabetic patients with ASB. One hundred and twenty-three patients with type 2 diabetes mellitus were included in the study. The patients were divided into two groups according to ASB; Group I consisted of 22 patients with ASB, and Group II of 101 patients without ASB. There were no significant differences between the groups in regard to age, body mass index, creatinine clearance or microalbuminuria, while there were significant differences in HbA1c, duration of diabetes mellitus, glucosuria and pyuria (P < 0.05). The most commonly isolated microorganism was Escherichia coli. The present study identified the duration of diabetes, high HbA1c, glucosuria and pyuria as risk factors for ASB in type 2 diabetic patients.
尿路感染在糖尿病患者中是一个严重问题，这些患者的无症状菌尿（ASB）是肾盂肾炎和肾功能不全的一个危险因素。在本研究中，我们调查了2型糖尿病合并ASB患者的年龄、体重指数、糖尿病病程、糖化血红蛋白水平、糖尿、肾小球滤过率和微量白蛋白尿之间的关系。123例2型糖尿病患者纳入本研究。根据是否存在ASB将患者分为两组；第一组由22例ASB患者组成，第二组由101例无ASB患者组成。两组在年龄、体重指数、肌酐清除率或微量白蛋白尿方面无显著差异，而在糖化血红蛋白、糖尿病病程、糖尿和脓尿方面存在显著差异（P<0.05）。最常分离出的微生物是大肠杆菌。本研究确定糖尿病病程、高糖化血红蛋白水平、糖尿和脓尿是2型糖尿病患者发生ASB的危险因素。
