Asadi-Pooya Ali A, Mintzer Scott, Sperling Michael R
Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Epilepsia. 2008 Nov;49(11):1819-27. doi: 10.1111/j.1528-1167.2008.01678.x. Epub 2008 May 21.
Anecdotal reports suggest that certain foods and dietary contents might influence the occurrence of seizures. However, the existing data are scanty and sometimes controversial. Some studies have found that the supplementation with individual nutrients reduced seizure frequency or improved other aspects of health in patients with epilepsy, while other studies have failed to confirm those findings. Nutrient supplementation may be necessary to prevent or reverse the effects of certain deficiencies that frequently result from the use of antiepileptic drugs (AEDs). However, the potential benefits of nutrient supplementation in patients with epilepsy must be weighed against reports that large doses of certain nutrients can interfere with the action of some AEDs. This paper reviews dietary and nutritional considerations in patients with epilepsy and also the relationship between foods, dietary elements, and seizures.
轶事报道表明，某些食物和饮食成分可能会影响癫痫发作的发生。然而，现有数据很少，有时还存在争议。一些研究发现，补充单一营养素可降低癫痫患者的发作频率或改善其健康的其他方面，而其他研究未能证实这些发现。补充营养素可能有必要预防或扭转某些因使用抗癫痫药物（AEDs）而经常导致的缺乏症的影响。然而，必须将补充营养素对癫痫患者的潜在益处与大量摄入某些营养素会干扰某些AEDs作用的报道进行权衡。本文综述了癫痫患者的饮食和营养方面的考虑因素，以及食物、饮食成分与癫痫发作之间的关系。
