Fielden Samuel W, Fornwalt Brandon K, Jerosch-Herold Michael, Eisner Robert L, Stillman Arthur E, Oshinski John N
Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
J Magn Reson Imaging. 2008 Jun;27(6):1382-7. doi: 10.1002/jmri.21387.
To evaluate the reproducibility of a new multisite axial pulse wave velocity (PWV) measurement technique that makes use of 2D PCMR data and cross-correlation analysis.
PWV was estimated with MRI in 13 healthy volunteers by a transit-time technique (TT), a multisite technique utilizing 1D PCMR data in the descending aorta (FOOT), and a new multisite axial technique that uses 2D PCMR data over the ascending, transverse, and descending sections of the aorta (2D-XC).
No significant difference was observed between PWV measurements values measured by the three techniques. However, 2D-XC displayed significantly better intertest reproducibility than either the TT or FOOT methodologies. Average percent difference between scans: TT: 15.8% +/- 13.4%, FOOT: 21.3% +/- 16.9%, 2D-XC: 7.72% +/- 4.73%. P = 0.02 for both 2D-XC/TT comparison and 2D-XC/FOOT comparison.
2D-XC is a more reproducible method than either the established TT or FOOT methods to estimate the aortic PWV.
评估一种利用二维相位对比磁共振(2D PCMR)数据和互相关分析的新型多部位轴向脉搏波速度(PWV)测量技术的可重复性。
采用磁共振成像(MRI),通过渡越时间技术(TT)、利用降主动脉一维PCMR数据的多部位技术(FOOT)以及一种在升主动脉、横主动脉和降主动脉节段使用二维PCMR数据的新型多部位轴向技术(2D-XC),对13名健康志愿者的PWV进行评估。
三种技术测量的PWV值之间未观察到显著差异。然而,2D-XC显示出比TT或FOOT方法显著更好的测试间可重复性。扫描间平均百分比差异:TT:15.8%±13.4%,FOOT:21.3%±16.9%,2D-XC:7.72%±4.73%。2D-XC/TT比较和2D-XC/FOOT比较的P值均为0.02。
与既定的TT或FOOT方法相比,2D-XC是一种更具可重复性的评估主动脉PWV的方法。