Zhang Lan-Zhen, Guo Ya-Jian, Tu Guang-Zhong, Shi Ren-Bing, Qin Wen, Ba Yin-Ying, Yang Fan
College of Traditional Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China.
Yao Xue Xue Bao. 2008 Feb;43(2):169-72.
To study the constituents of the Prunella vulgaris L, the constituents were isolated by various column chromatography and the structures were identified on the basis of chemical and spectral analysis. One saponin compound (I) and one flavone glycoside compound (II) were obtained from Prunella vulgaris L. Their structures were elucidated as 16-oxo-17-demethyl-3beta,24-dihydroxylolean-12-en-3-O-beta-D-glucuronoside (I), and acacetin-7-O-beta-D-glucopyranoside (II). Compound I is a novel triterpenoid saponin and named as prunelloside A. Compound II was obtained for the first time from the Prunella genus.
为研究夏枯草的成分，采用多种柱色谱法对其成分进行分离，并通过化学和光谱分析鉴定其结构。从夏枯草中得到了1个皂苷化合物（I）和1个黄酮苷化合物（II）。其结构经确认为16-氧代-17-去甲基-3β,24-二羟基齐墩果-12-烯-3-O-β-D-葡萄糖醛酸苷（I）和刺槐素-7-O-β-D-吡喃葡萄糖苷（II）。化合物I是一种新型三萜皂苷，命名为夏枯皂苷A。化合物II首次从夏枯草属植物中获得。
